Synchrotron radiation induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen. (Q39397685)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Synchrotron radiation induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

main subject

synchrotron radiation

0 references

author

Peter A. Lay

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Paul K Witting

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Hugh H. Harris

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Stefan Vogt

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Greg Giles

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Jade B Aitken

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

T T Hong Duong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Roshanak Aran

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Barry Lai

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

publication date

11 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Inorganic Chemistry

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

589-598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00775-012-0879-y

22 January 2020

exact match

0 references

cites work

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Chemistry of biologically important synthetic organoselenium compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Redox catalysts as sensitisers towards oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Targeting oxidative stress-related diseases: organochalcogen catalysts as redox sensitizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Multifunctional redox catalysts as selective enhancers of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen, a seleno-organic antioxidant, is neuroprotective after embolic strokes in rabbits: synergism with low-dose tissue plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen, a selenium-containing redox drug, releases zinc from metallothionein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Selenium compounds modulate the calcium release channel/ryanodine receptor of rabbit skeletal muscle by oxidizing functional thiols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Interaction of selenium compounds with zinc finger proteins involved in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen, a seleno-organic antioxidant, as an electrophile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen augments its peroxidase activity by inducing nrf-2-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Recent approaches to intracellular delivery of drugs and DNA and organelle targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

X-ray fluorescence microscopy reveals the role of selenium in spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Studies on the biotransformations and biodistributions of metal-containing drugs using X-ray absorption spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Silicon nitride as a versatile growth substrate for microspectroscopic imaging and mapping of individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

The endothelium-derived hyperpolarizing factor, H2O2, promotes metal-ion efflux in aortic endothelial cells: elemental mapping by a hard X-ray microprobe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Time-dependent uptake, distribution and biotransformation of chromium(VI) in individual and bulk human lung cells: application of synchrotron radiation techniques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Intracellular mapping of the distribution of metals derived from the antitumor metallocenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Hard X-ray microprobe studies of chromium(VI)-treated V79 Chinese hamster lung cells: intracellular mapping of the biotransformation products of a chromium carcinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Linking stress-signaling, glutathione metabolism, signaling pathways and xenobiotic transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Translational mobility of the type 3 inositol 1,4,5-trisphosphate receptor Ca2+ release channel in endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

An introduction to thiol redox proteins in the endoplasmic reticulum and a review of current electrochemical methods of detection of thiols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Ebselen has dehydroascorbate reductase and thioltransferase-like activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

A genomic screen for activators of the antioxidant response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

The transcriptional activation of the human copper/zinc superoxide dismutase gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin through two different regulator sites, the antioxidant responsive element and xenobiotic responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

(-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Zinc proteins: enzymes, storage proteins, transcription factors, and replication proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Solution structure of a functional biomimetic and mechanistic implications for nickel superoxide dismutases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Biomedical applications of X-ray absorption and vibrational spectroscopic microscopies in obtaining structural information from complex systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

A novel biologically active seleno-organic compound—1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-012-0879-Y

Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.

21 January 2018

1 reference

12 December 2020

Electrochemistry of chalcogen compounds: prediction of antioxidant activity.

1 reference

12 December 2020

A chemical strategy to manipulate the intracellular localization of drugs in resistant cancer cells

1 reference

12 December 2020

Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C?

1 reference

12 December 2020

Electrochemical, in vitro and cell culture analysis of integrated redox catalysts: implications for cancer therapy

1 reference

12 December 2020

Mechanism of the reaction of ebselen with endogenous thiols: dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen

1 reference

12 December 2020

The glutathione peroxidases

1 reference

12 December 2020

The inhibition of mammalian 15-lipoxygenases by the anti-inflammatory drug ebselen: dual-type mechanism involving covalent linkage and alteration of the iron ligand sphere.

1 reference

12 December 2020

10.1007/S00775-012-0879-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22327627%20AND%20SRC:MED&resulttype=core&format=json

release_glbroqxmzff4zbge5heqyrcp2i

22 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/glbroqxmzff4zbge5heqyrcp2i

24 November 2022

mapped directly with Wikidata item

1 reference