Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β. (Q39376769)

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English	Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β.	scientific article

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26 January 2020

Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β (English)

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26 January 2020

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26 January 2020

author name string

Yoko Katsuno

1

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26 January 2020

Masakazu Yashiro

3

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26 January 2020

Kazuyoshi Yanagihara

4

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26 January 2020

Kosei Hirakawa

5

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26 January 2020

Kohei Miyazono

6

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8 May 2012

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26 January 2020

Journal of Pathology

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26 January 2020

228

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3

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26 January 2020

391-404

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26 January 2020

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

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Epidemiology of gastric cancer

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Role of orthotopic fibroblasts in the development of scirrhous gastric carcinoma.

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Establishment of lymph node metastatic model for human gastric cancer in nude mice and analysis of factors associated with metastasis

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Peritoneal metastatic model for human scirrhous gastric carcinoma in nude mice

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Establishment and characterization of a human gastric scirrhous carcinoma cell line in serum-free chemically defined medium

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Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma

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Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.

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Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.

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Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim.

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Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway

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Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma

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21 January 2018

Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas

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Overexpression of Reg IV in colorectal adenoma

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The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target

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Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer

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Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas

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21 January 2018

Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling

1 reference

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21 January 2018

c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma.

1 reference

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21 January 2018

Two major Smad pathways in TGF-beta superfamily signalling.

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Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer

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Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV.

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Gene expression profile of gastric carcinoma: identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression

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Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy

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Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis

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Evaluation of REG4 for early diagnosis and prognosis of gastric cancer.

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Roles of TGF-beta family signaling in stem cell renewal and differentiation

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The epithelial-mesenchymal transition generates cells with properties of stem cells

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Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

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Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

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TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma.

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Identifiers

10.1002/PATH.4020

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26 January 2020

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