Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics. (Q39369866)

11 September 2017

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title

Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

alternative mRNA splicing, via spliceosome

11 May 2020

main subject

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

Peter Scheiffele

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

author name string

Oriane Mauger

series ordinal

1

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PubMed ID

28609697

11 September 2017

Peter Scheiffele

series ordinal

2

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11 September 2017

10 June 2017

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Current Opinion in Neurobiology

11 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

volume

45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

page(s)

162-168

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

11 May 2020

cites work

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12 December 2020

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

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12 December 2020

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

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12 December 2020

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

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12 December 2020

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

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12 December 2020

The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression

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12 December 2020

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

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12 December 2020

Rapid, transcript-specific changes in splicing in response to environmental stress

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12 December 2020

Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion

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12 December 2020

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

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12 December 2020

Rates of in situ transcription and splicing in large human genes

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12 December 2020

The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.

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12 December 2020

Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay

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12 December 2020

Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast

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12 December 2020

Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor

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12 December 2020

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.

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12 December 2020

Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration

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12 December 2020

Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention

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12 December 2020

The evolutionary landscape of alternative splicing in vertebrate species

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12 December 2020

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

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12 December 2020

Removal of retained introns regulates translation in the rapidly developing gametophyte of Marsilea vestita

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12 December 2020

Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay

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12 December 2020

Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing

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12 December 2020

Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking

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12 December 2020

Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity

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12 December 2020

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis.

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12 December 2020

Probabilistic splicing of Dscam1 establishes identity at the level of single neurons.

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12 December 2020

Quality control of spliced mRNAs requires the shuttling SR proteins Gbp2 and Hrb1.

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12 December 2020

Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway

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12 December 2020

Widespread inhibition of posttranscriptional splicing shapes the cellular transcriptome following heat shock

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12 December 2020

EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia

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12 December 2020

Intracellular calcium regulates nonsense-mediated mRNA decay

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12 December 2020

Widespread intron retention in mammals functionally tunes transcriptomes

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12 December 2020

Targeted combinatorial alternative splicing generates brain region-specific repertoires of neurexins.

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12 December 2020

Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins.

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12 December 2020

Detained introns are a novel, widespread class of post-transcriptionally spliced introns

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12 December 2020

Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

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12 December 2020

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

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12 December 2020

Recursive splicing in long vertebrate genes

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12 December 2020

Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes

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12 December 2020

Non-coding functions of alternative pre-mRNA splicing in development

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12 December 2020

Mutation of genes controlling mRNA metabolism and protein synthesis predisposes to neurodevelopmental disorders

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12 December 2020

Control of Transcript Variability in Single Mammalian Cells.

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12 December 2020

Nuclear Retention of mRNA in Mammalian Tissues

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12 December 2020

The regulation and functions of the nuclear RNA exosome complex.

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12 December 2020

The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay

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12 December 2020

Control of neuronal synapse specification by a highly dedicated alternative splicing program.

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12 December 2020

Neurodegeneration and RNA-binding proteins

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12 December 2020

An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus

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12 December 2020

Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.

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12 December 2020

Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells.

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12 December 2020

10.1016/J.CONB.2017.05.012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6689270&resulttype=core&format=json

11 May 2020

1 reference