Alzheimer Aβ peptide interactions with lipid membranes: fibrils, oligomers and polymorphic amyloid channels. (Q39330775)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Alzheimer Aβ peptide interactions with lipid membranes: fibrils, oligomers and polymorphic amyloid channels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

Nicolae-Viorel Buchete

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

author name string

Florentina Tofoleanu

series ordinal

1

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10 February 2020

publication date

9 August 2012

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10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

6

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10 February 2020

issue

4

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10 February 2020

page(s)

339-345

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

Are Peptides Good Two-State Folders?

10 February 2020

cites work

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Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships

11 September 2017

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Atomic View of a Toxic Amyloid Small Oligomer

11 September 2017

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The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane

11 September 2017

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Oligomeric intermediates in amyloid formation: structure determination and mechanisms of toxicity

11 September 2017

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Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology

11 September 2017

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Amphiphilic adsorption of human islet amyloid polypeptide aggregates to lipid/aqueous interfaces

11 September 2017

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Lipid matrix plays a role in Abeta fibril kinetics and morphology

11 September 2017

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Evidence from solid-state NMR for nonhelical conformations in the transmembrane domain of the amyloid precursor protein

11 September 2017

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β-Barrel topology of Alzheimer's β-amyloid ion channels

11 September 2017

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Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

11 September 2017

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Dynamics of protein folding: probing the kinetic network of folding-unfolding transitions with experiment and theory.

11 September 2017

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Structures of beta-amyloid peptide 1-40, 1-42, and 1-55-the 672-726 fragment of APP-in a membrane environment with implications for interactions with gamma-secretase

11 September 2017

1 reference

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Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

11 September 2017

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Transmembrane structures of amyloid precursor protein dimer predicted by replica-exchange molecular dynamics simulations

11 September 2017

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Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

11 September 2017

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New structures help the modeling of toxic amyloidbeta ion channels

11 September 2017

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Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

11 September 2017

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Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process

11 September 2017

1 reference

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Structure and dynamics of parallel beta-sheets, hydrophobic core, and loops in Alzheimer's A beta fibrils

11 September 2017

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Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

11 September 2017

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Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide

11 September 2017

1 reference

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The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding

11 September 2017

1 reference

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Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

11 September 2017

1 reference

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Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

11 September 2017

1 reference

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Amyloid ion channels: a common structural link for protein-misfolding disease

11 September 2017

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Conformational transition of amyloid beta-peptide

11 September 2017

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Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

11 September 2017

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Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide

11 September 2017

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

11 September 2017

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Computational studies of membrane channels

11 September 2017

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Electrostatic Tuning of Permeation and Selectivity in Aquaporin Water Channels

11 September 2017

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

11 September 2017

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Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain

11 September 2017

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Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

11 September 2017

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A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state

11 September 2017

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The Alzheimer's peptide a beta adopts a collapsed coil structure in water

11 September 2017

1 reference

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Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

11 September 2017

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Amyloid beta protein-(1-42) forms calcium-permeable, Zn2+-sensitive channel

11 September 2017

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Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease

11 September 2017

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Theoretical models of the ion channel structure of amyloid beta-protein

11 September 2017

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

11 September 2017

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Genetics and biology of the Alzheimer amyloid precursor

11 September 2017

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Methodological variables in the assessment of beta amyloid neurotoxicity

11 September 2017

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beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease

11 September 2017

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Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity

14 September 2017

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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

25 September 2017

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Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

25 September 2017

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Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores.

15 June 2018

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Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

15 June 2018

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

15 June 2018

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Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

15 June 2018

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Conformational dynamics of human IAPP monomers

17 June 2018

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Cholesterol promotes the interaction of Alzheimer β-amyloid monomer with lipid bilayer.

21 August 2018

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Medicine. Prion-like behavior of amyloid-beta.

21 August 2018

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Efficiency of histidine-associating compounds for blocking the alzheimer's Abeta channel activity and cytotoxicity

21 August 2018

1 reference

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Metal effects on the membrane interactions of amyloid-beta peptides

21 August 2018

1 reference

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Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.

21 August 2018

1 reference

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 August 2018

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Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers.

21 August 2018

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Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 August 2018

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Molecular Interactions of Alzheimer's Aβ Protofilaments with Lipid Membranes

21 August 2018

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Crossref

https://api.crossref.org/works/10.4161%2FPRI.21022

Dissecting contact potentials for proteins: Relative contributions of individual amino acids

21 January 2018

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https://api.crossref.org/works/10.4161%2FPRI.21022

β-Sheet Structured β-Amyloid(1-40) Perturbs Phosphatidylcholine Model Membranes

21 January 2018

1 reference

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https://api.crossref.org/works/10.4161%2FPRI.21022

Shedding light on Alzheimer's β-amyloid aggregation with chemical tools

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22874669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Early and late cytotoxic effects of external application of the Alzheimer's Abeta result from the initial formation and function of Abeta ion channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22874669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22874669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/PRI.21022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22874669%20AND%20SRC:MED&resulttype=core&format=json