Pentoxifylline inhibits hepatic stellate cells proliferation via the Raf/ERK pathway (Q39328005)

11 September 2017

Pentoxifylline inhibits hepatic stellate cells proliferation via the Raf/ERK pathway (English)

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11 September 2017

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Di Zhang

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11 September 2017

Huiqing Jiang

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2

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11 September 2017

Yan Wang

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3

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11 September 2017

Junji Ma

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4

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11 September 2017

language of work or name

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19 January 2012

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Acta Pathologica et Microbiologica Scandinavica

11 September 2017

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11 September 2017

120

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11 September 2017

7

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11 September 2017

572-581

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Hepatic fibrosis: molecular mechanisms and drug targets

11 September 2017

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Mechanisms of hepatic fibrogenesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Genomics of liver fibrosis and cirrhosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Hepatic stellate cell proliferation is an early platelet-derived growth factor-mediated cellular event in rat cholestatic liver injury

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Role of rab5 in EGF receptor-mediated signal transduction

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

As2O3-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21WAF1/CIP1 expression in human epidermoid carcinoma A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Effects of phosphodiesterase inhibition on the inflammatory response after shock: role of pentoxifylline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Nonspecific phosphodiesterase inhibition attenuates liver injury in acute endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: effects on tight junction structural proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Anandamide induces necrosis in primary hepatic stellate cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Phosphatidylinositol 3-kinase/Akt pathway regulates hepatic stellate cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Immunomodulatory effect of pentoxifylline in suppressing experimental autoimmune myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Pentoxifylline inhibits PDGF-induced proliferation of and TGF-beta-stimulated collagen synthesis by vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Inhibition of endothelial cell proliferation and tumor-induced angiogenesis by pentoxifylline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Pentoxifylline prevents pig serum-induced rat liver fibrosis by inhibiting interleukin-6 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

The phyto-chemical (-)-epigallocatechin gallate suppresses gene expression of epidermal growth factor receptor in rat hepatic stellate cells in vitro by reducing the activity of Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Activation of cytosolic phospholipase A2alpha by epidermal growth factor (EGF) and phorbol ester in HeLa cells: different effects of inhibitors for EGF receptor, protein kinase C, Src, and C-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21Ras in H9C2 cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

EGF induces cell motility and multi-drug resistance gene expression in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Predictive and prognostic biomarkers for targeted therapy in metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Pentoxifylline modulates p47phox activation and downregulates neutrophil oxidative burst through PKA-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Cell signaling through the protein kinases cAMP-dependent protein kinase, protein kinase Cepsilon, and RAF-1 regulates amphotropic murine leukemia virus envelope protein-induced syncytium formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Inhibition by pentoxifylline of extracellular signal-regulated kinase activation by platelet-derived growth factor in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Blocking of Akt/NF-kappaB signaling by pentoxifylline inhibits platelet-derived growth factor-stimulated proliferation in Brown Norway rat airway smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Modulation of DNA damage by pentoxifylline and alpha-tocopherol in skin fibroblasts exposed to Gamma rays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

Antiapoptotic and proliferative effects of low concentrations of 7β-hydroxycholesterol in human endothelial cells via ERK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0463.2011.02868.X

10.1111/J.1600-0463.2011.02868.X

21 January 2018

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11 September 2017

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