Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras. (Q39321689)

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English	Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras.	scientific article

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4 January 2020

Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras (English)

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4 January 2020

Alasdair J Gibb

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4 January 2020

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V J Gee

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S Kracun

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S T Cooper

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N S Millar

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27 August 2007

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4 January 2020

British Journal of Pharmacology

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4 January 2020

RIC-3 enhances functional expression of multiple nicotinic acetylcholine receptor subtypes in mammalian cells.

1 reference

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11 September 2017

Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors

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11 September 2017

Ric-3 promotes functional expression of the nicotinic acetylcholine receptor alpha7 subunit in mammalian cells

1 reference

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11 September 2017

Assembly and subunit diversity of nicotinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

11 September 2017

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

1 reference

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11 September 2017

The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences

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11 September 2017

The calcium sensor protein visinin-like protein-1 modulates the surface expression and agonist sensitivity of the alpha 4beta 2 nicotinic acetylcholine receptor

1 reference

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11 September 2017

Role of the large cytoplasmic loop of the alpha 7 neuronal nicotinic acetylcholine receptor subunit in receptor expression and function

1 reference

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11 September 2017

Open probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancy

1 reference

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11 September 2017

The chaperone protein 14-3-3eta interacts with the nicotinic acetylcholine receptor alpha 4 subunit. Evidence for a dynamic role in subunit stabilization

1 reference

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11 September 2017

Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers

1 reference

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Presynaptic ionotropic receptors and the control of transmitter release.

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11 September 2017

Host cell-specific folding of the neuronal nicotinic receptor alpha8 subunit

1 reference

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11 September 2017

Functional contribution of the alpha7 subunit to multiple subtypes of nicotinic receptors in embryonic chick sympathetic neurones.

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11 September 2017

Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites

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11 September 2017

A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors.

1 reference

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11 September 2017

Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers

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11 September 2017

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium.

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11 September 2017

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

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11 September 2017

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

11 September 2017

The fall and rise of neuronal alpha-bungarotoxin binding proteins

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11 September 2017

The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors

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14 September 2017

Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.

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14 September 2017

Molecular characterization of Dalpha6 and Dalpha7 nicotinic acetylcholine receptor subunits from Drosophila: formation of a high-affinity alpha-bungarotoxin binding site revealed by expression of subunit chimeras

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14 September 2017

Pharmacological properties of alpha 9 alpha 10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras

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14 September 2017

Functional properties of homomeric, human alpha 7-nicotinic acetylcholine receptors heterologously expressed in the SH-EP1 human epithelial cell line

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14 September 2017

Amino acid determinants of alpha 7 nicotinic acetylcholine receptor surface expression

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25 September 2017

The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors

1 reference

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25 September 2017

The intracellular domain of the nicotinic acetylcholine receptor alpha subunit mediates its coclustering with rapsyn

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25 September 2017

Up-regulation of cell-surface alpha4beta2 neuronal nicotinic receptors by lower temperature and expression of chimeric subunits

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25 September 2017

Identification of residues in the neuronal alpha7 acetylcholine receptor that confer selectivity for conotoxin ImI.

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Differences in the fate of neuronal acetylcholine receptor protein expressed in neurons and stably transfected cells

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25 September 2017

Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor alpha7 subunit

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25 September 2017

A sequence in the main cytoplasmic loop of the alpha subunit is required for assembly of mouse muscle nicotinic acetylcholine receptor

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25 September 2017

Functional expression of nicotinic acetylcholine receptors containing rat alpha 7 subunits in human SH-SY5Y neuroblastoma cells

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Ca2+ permeability of cloned and native 5-hydroxytryptamine type 3 receptors.

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25 September 2017

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

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25 September 2017

Guide to Receptors and Channels (GRAC), 2nd edition (2007 Revision).

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17 June 2018

Functional nicotinic ACh receptors on interneurones in the rat hippocampus.

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17 June 2018

Detection of functional nicotinic receptors blocked by alpha-bungarotoxin on PC12 cells and dependence of their expression on post-translational events

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17 June 2018

Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

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17 June 2018

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

17 June 2018

Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel

1 reference

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17 June 2018

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

17 June 2018

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

17 June 2018

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

17 June 2018

The long internal loop of the alpha 3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

Neuronal alpha-bungarotoxin receptors differ structurally from other nicotinic acetylcholine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050819

21 August 2018

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17721553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/17721553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/17721553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17721553

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707429

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJP.0707429

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17721553%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17721553%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17721553%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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