Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations (Q39320300)

11 September 2017

Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations (English)

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11 September 2017

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Christine Van Broeckhoven

11 September 2017

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Van Broeckhoven C

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Ishii K

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Usami M

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Sahara N

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Kametani F

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Tanaka K

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Fraser PE

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Ikeda M

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Saunders AM

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Hendriks L

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Shoji SI

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Nee LE

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Martin JJ

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St George-Hyslop PH

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Roses AD

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Mori H

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11 September 2017

language of work or name

English

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publication date

1 November 1997

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11 September 2017

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418

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162-166

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1-2

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

11 September 2017

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Different effects of Alzheimer-associated mutations of presenilin 1 on its processing

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Abnormal gel-electrophoretic behavior of presenilin 1 and it's fragment

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Identification and characterization of presenilin I-467, I-463 and I-374.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Human ICE/CED-3 protease nomenclature

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Protease activation during apoptosis: death by a thousand cuts?

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Presenilins are processed by caspase-type proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

Protein topology of presenilin 1

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2901378-1

10.1016/S0014-5793(97)01378-1

21 January 2018

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DOI

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11 September 2017

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