Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease (Q39315870)

30 June 2018

review article

1 reference

title

Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease (English)

1 reference

30 June 2018

author name string

Chirag H Patel

series ordinal

1

1 reference

30 June 2018

Jonathan D Powell

series ordinal

2

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30 June 2018

publication date

15 May 2017

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30 June 2018

Current Opinion in Immunology

published in

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30 June 2018

volume

46

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30 June 2018

page(s)

82-88

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30 June 2018

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

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Targeting glutamine metabolism rescues mice from late-stage cerebral malaria

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T cell metabolism drives immunity

3 July 2018

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3 July 2018

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mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation

3 July 2018

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Normalization of CD4+ T cell metabolism reverses lupus

3 July 2018

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3 July 2018

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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

3 July 2018

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Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

3 July 2018

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The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

3 July 2018

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Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation

3 July 2018

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T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

3 July 2018

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Small molecule glutaminase inhibitors block glutamate release from stimulated microglia

3 July 2018

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Fueling immunity: insights into metabolism and lymphocyte function

3 July 2018

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

3 July 2018

1 reference

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Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

3 July 2018

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CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.

3 July 2018

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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

3 July 2018

1 reference

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Posttranscriptional control of T cell effector function by aerobic glycolysis

3 July 2018

1 reference

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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

3 July 2018

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

3 July 2018

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Metabolic regulation of T lymphocytes

3 July 2018

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mTOR, metabolism, and the regulation of T-cell differentiation and function

3 July 2018

1 reference

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Metabolic switching and fuel choice during T-cell differentiation and memory development

3 July 2018

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

3 July 2018

1 reference

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Regulation of immune responses by mTOR.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

mTOR regulates memory CD8 T-cell differentiation

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

The CD28 signaling pathway regulates glucose metabolism

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554728

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28521236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.COI.2017.04.006

1 reference

30 June 2018

PMCID

5554728

1 reference

30 June 2018

PubMed ID

28521236

1 reference

30 June 2018