With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia (Q39308848)

10 September 2017

5 references

23 March 2019

12 October 2019

18 October 2019

22 August 2020

29 October 2020

With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia (English)

1 reference

10 September 2017

5 references

23 March 2019

12 October 2019

18 October 2019

22 August 2020

29 October 2020

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

22 August 2020

1 reference

29 October 2020

Roger D Pechous

1

1 reference

PMCID

5410563

10 September 2017

language of work or name

1 reference

1 May 2017

6 references

Frontiers in Cellular and Infection Microbiology

10 September 2017

23 March 2019

12 October 2019

18 October 2019

22 August 2020

29 October 2020

6 references

10 September 2017

23 March 2019

12 October 2019

18 October 2019

22 August 2020

29 October 2020

7

1 reference

10 September 2017

160

1 reference

Creative Commons Attribution 4.0 International

10 September 2017

5 references

23 March 2019

12 October 2019

18 October 2019

22 August 2020

on focus list of Wikimedia project

29 October 2020

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copyrighted

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ScienceSource

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cites work

Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epithelium

1 reference

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S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin.

11 September 2017

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The NADPH Oxidase and Microbial Killing by Neutrophils, With a Particular Emphasis on the Proposed Antimicrobial Role of Myeloperoxidase within the Phagocytic Vacuole

11 September 2017

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Neutrophil Extracellular Traps in Pulmonary Diseases: Too Much of a Good Thing?

11 September 2017

1 reference

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Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia.

11 September 2017

1 reference

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Relevant Cytokines in the Management of Community-Acquired Pneumonia

11 September 2017

1 reference

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Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague

11 September 2017

1 reference

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Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment

11 September 2017

1 reference

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In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation

11 September 2017

1 reference

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Lipid mediators in the resolution of inflammation

11 September 2017

1 reference

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Neutrophil elastase causes tissue damage that decreases host tolerance to lung infection with burkholderia species

11 September 2017

1 reference

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Dynamics of lung defense in pneumonia: resistance, resilience, and remodeling.

11 September 2017

1 reference

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Early host cell targets of Yersinia pestis during primary pneumonic plague

11 September 2017

1 reference

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Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation

11 September 2017

1 reference

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A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection

11 September 2017

1 reference

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Neutrophil recruitment and function in health and inflammation

11 September 2017

1 reference

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CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin

11 September 2017

1 reference

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Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice

11 September 2017

1 reference

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Respiratory infection and the impact of pulmonary immunity on lung health and disease

11 September 2017

1 reference

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Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones

11 September 2017

1 reference

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Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

11 September 2017

1 reference

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Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis

11 September 2017

1 reference

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Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Contribution of neutrophils to acute lung injury

11 September 2017

1 reference

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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

11 September 2017

1 reference

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In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation.

11 September 2017

1 reference

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CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection

11 September 2017

1 reference

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Nonresolving inflammation

11 September 2017

1 reference

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Human defensins and LL-37 in mucosal immunity.

11 September 2017

1 reference

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Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil recruitment to the lungs during bacterial pneumonia

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

The role of the multifunctional peptide LL-37 in host defense

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Acute lower respiratory tract infection

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Beneficial suicide: why neutrophils die to make NETs

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil granules: a library of innate immunity proteins

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil serine proteases: specific regulators of inflammation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophils and immunity: challenges and opportunities

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Lung infection--a public health priority

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil granule contents in the pathogenesis of lung injury

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Pulmonary defense and the human cathelicidin hCAP-18/LL-37.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Myeloperoxidase: friend and foe

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Transcriptional profiling of lipopolysaccharide-induced acute lung injury

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil extracellular traps kill bacteria

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil elastase induces IL-8 synthesis by lung epithelial cells via the mitogen-activated protein kinase pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophils and lung injury: getting it right

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil elastase targets virulence factors of enterobacteria

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil activation and acute lung injury.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Lactoferrin: a general review.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

In vivo damage of rat lungs by oxygen metabolites

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. II. Cytochemistry and electron microscopy of bone marrow cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. I. Histochemical staining of bone marrow smears

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Lactoferrin immunomodulation of DTH response in mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil-mediated epithelial injury during transmigration: role of elastase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Infection regulates pro-resolving mediators that lower antibiotic requirements

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

In vivo efficacy of KRP-109, a novel elastase inhibitor, in a murine model of severe pneumococcal pneumonia.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Human neutrophils kill Streptococcus pneumoniae via serine proteases.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Regulation of reactive oxygen species-induced endothelial cell-cell and cell-matrix contacts by focal adhesion kinase and adherens junction proteins

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

High concentrations of alpha-defensins in plasma and bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Membrane expression of proteinase 3 is genetically determined

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Inherited Neutrophil Disorders: Molecular Basis and New Therapies

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Pulmonary epithelial cells facilitate TNF-alpha-induced neutrophil chemotaxis. A role for cytokine networking.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410563

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389%2FFCIMB.2017.00160

Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps

21 January 2018

1 reference

12 December 2020

Severe community-acquired pneumonia

1 reference

12 December 2020

Differential effects of alpha- and beta-defensin on cytokine production by cultured human bronchial epithelial cells

1 reference

12 December 2020

TNF-alpha-induced transendothelial neutrophil migration is IL-8 dependent

1 reference

12 December 2020

Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa

1 reference

12 December 2020

Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

1 reference

12 December 2020

Fatal (chronic) granulomatous disease of childhood: a hereditary defect of leukocyte function

1 reference

12 December 2020

Nonisotropic enzyme--inhibitor interactions: a novel nonoxidative mechanism for quantum proteolysis by human neutrophils

1 reference

12 December 2020

The importance of neutrophils in resistance to pneumococcal pneumonia in adult and neonatal mice

1 reference

12 December 2020

Delayed neutrophil elastase inhibition prevents subsequent progression of acute lung injury induced by endotoxin inhalation in hamsters

1 reference

12 December 2020

Identifiers

DOI

10.3389/FCIMB.2017.00160

1 reference

10 September 2017

1 reference

10 September 2017

1 reference

PMCID

5410563