Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis (Q39305976)

10 September 2017

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis (English)

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10 September 2017

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X Li

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10 September 2017

V Placencio

2

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10 September 2017

J M Iturregui

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10 September 2017

C Uwamariya

4

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10 September 2017

A-R Sharif-Afshar

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10 September 2017

T Koyama

6

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10 September 2017

S W Hayward

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10 September 2017

N A Bhowmick

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10 September 2017

language of work or name

English

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publication date

25 August 2008

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10 September 2017

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27

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10 September 2017

7118-7130

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56

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https://scigraph.springernature.com/pub.10.1038/onc.2008.293

10 September 2017

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cites work

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Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

11 September 2017

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Wnt/beta-catenin signaling in development and disease

11 September 2017

1 reference

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Diseases of Wnt signaling

11 September 2017

1 reference

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Roles and regulation of Wnt signaling and beta-catenin in prostate cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Wnt signalling and prostate cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Role of transforming growth factor Beta in human cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Tumor-stroma interactions

11 September 2017

1 reference

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Stromal fibroblasts in cancer initiation and progression

11 September 2017

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Role of p63 and basal cells in the prostate

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.

11 September 2017

1 reference

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

11 September 2017

1 reference

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The two faces of transforming growth factor beta in carcinogenesis

11 September 2017

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

11 September 2017

1 reference

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Role of transforming growth factor beta in cancer

11 September 2017

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

11 September 2017

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beta-catenin signaling and cancer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Identification of c-MYC as a target of the APC pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Loss of expression of transforming growth factor-beta receptors is associated with poor prognosis in prostate cancer patients

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Serum-free culture of enriched mouse anterior and ventral prostatic epithelial cells in collagen gel.

11 September 2017

1 reference

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Prostatic intraepithelial neoplasia is a risk factor for adenocarcinoma: predictive accuracy in needle biopsies

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate

14 September 2017

1 reference

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Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival

14 September 2017

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Malignant transformation in a nontumorigenic human prostatic epithelial cell line.

25 September 2017

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Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

25 September 2017

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Cytoskeletal reorganization by soluble Wnt-3a protein signalling

25 September 2017

1 reference

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Sex hormone-induced carcinogenesis in Rb-deficient prostate tissue

25 September 2017

1 reference

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Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis.

15 June 2018

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Transforming growth factor beta 1 and its receptor types I and II. Comparison in human normal prostate, benign prostatic hyperplasia, and prostatic carcinoma

15 June 2018

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Localization of transforming growth factor-beta1 and type II receptor in developing normal human prostate and carcinoma tissues

15 June 2018

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In situ analysis of transforming growth factor-beta s (TGF-beta 1, TGF-beta 2, TGF-beta 3), and TGF-beta type II receptor expression in malignant melanoma.

15 June 2018

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Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Characterization of antibodies to androgen-dependent secretory proteins of the mouse dorsolateral prostate

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

A new nomenclature for int-1 and related genes: the Wnt gene family

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Effects of mesenchyme of the embryonic urogenital sinus and neonatal seminal vesicle on the cytodifferentiation of the Dunning tumor: ultrastructural study.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

A functional model of adult human prostate epithelium. The role of androgens and stroma in architectural organisation and the maintenance of differentiated secretory function

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

21 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.

21 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Beta-catenin mutations in human prostate cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3222150

Significance of TWIST expression and its association with E-cadherin in bladder cancer

21 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.293

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.293

Prognostic significance of transforming growth factor beta receptor II in estrogen receptor-negative breast cancer patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.293

Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of theTGRβRII,BAX,hMSH3,hMSH6,IGFIIR andBLM genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.293

The induction of adenocarcinomatous differentiation in neoplastic bladder epithelium by an embryonic prostatic inductor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.293

Transforming growth factor-beta expression in prostate neoplasia

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18724388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18724388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2008.293

1 reference

10 September 2017

1 reference

10 September 2017

1 reference