Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin (Q39285748)

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scientific article published on 4 September 2012

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English	Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin	scientific article published on 4 September 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

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author name string

Rong-rong Tao

1

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PubMed publication ID

10 September 2017

Ji-Yun Huang

2

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10 September 2017

Xue-jing Shao

3

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10 September 2017

Wei-feng Ye

4

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10 September 2017

Yun Tian

5

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10 September 2017

Mei-hua Liao

6

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10 September 2017

Kohji Fukunaga

7

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10 September 2017

Yi-jia Lou

8

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10 September 2017

Feng Han

9

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10 September 2017

Ying-mei Lu

10

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10 September 2017

publication date

4 September 2012

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10 September 2017

Journal of Pineal Research

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10 September 2017

54

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10 September 2017

3

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10 September 2017

271-281

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10 September 2017

The neurovascular link in health and disease: molecular mechanisms and therapeutic implications

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

The neurovascular unit, matrix proteases, and innate inflammation

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Brain endothelial cell death: modes, signaling pathways, and relevance to neural development, homeostasis, and disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Biology of vascular malformations of the brain

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Modulation of oxidant and antioxidant enzyme expression and function in vascular cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Microsphere embolism-induced endothelial nitric oxide synthase expression mediates disruption of the blood-brain barrier in rat brain.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Nuclear matrix protein (NRP/B) modulates the nuclear factor (Erythroid-derived 2)-related 2 (NRF2)-dependent oxidative stress response

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin ameliorates ischemic-like injury-evoked nitrosative stress: Involvement of HtrA2/PED pathways in endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Targeting nitrosative stress for neurovascular protection: new implications in brain diseases

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Detection of protein S-nitrosylation with the biotin-switch technique

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

17beta-Estradiol induces protein S-nitrosylation in the endothelium

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Degradation of PEP-19, a calmodulin-binding protein, by calpain is implicated in neuronal cell death induced by intracellular Ca2+ overload

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: mitochondria as the major target

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin treatment following stroke induction modulates L-arginine metabolism.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Keap1 modification and nuclear accumulation in response to S-nitrosocysteine

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Melatonin is a scavenger of peroxynitrite

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Nrf2:INrf2 (Keap1) signaling in oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12009

21 January 2018

Identifiers

10.1111/JPI.12009

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 September 2017

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