Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP. (Q39282242)

10 September 2017

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP. (English)

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10 September 2017

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Bo-Shi Wang

1

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10 September 2017

Yi-Zhen Liu

2

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10 September 2017

Yang Yang

3

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10 September 2017

Yu Zhang

4

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10 September 2017

Jia-Jie Hao

5

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10 September 2017

Hai Yang

6

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10 September 2017

Xiao-Min Wang

7

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10 September 2017

Zi-Qiang Zhang

8

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10 September 2017

Qi-Min Zhan

9

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10 September 2017

Ming-Rong Wang

10

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10 September 2017

language of work or name

English

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publication date

1 February 2013

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10 September 2017

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10 September 2017

124

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10 September 2017

3

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203-214

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Role and regulation of autophagy in cancer

10 September 2017

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https://api.crossref.org/works/10.1042%2FCS20120270

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Anti- and pro-tumor functions of autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Selective autophagy mediated by autophagic adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Selective autophagy in cancer development and therapy

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Characterization of 21 newly established esophageal cancer cell lines

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Prognostic significance of MCM7 expression in the bronchial brushings of patients with non-small cell lung cancer (NSCLC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

The selectivity of autophagy and its role in cell death and survival

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Identifying the estrogen receptor coactivator PELP1 in autophagosomes.

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10.

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Selective degradation of p62 by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Activation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Conditional expression of oncogenic C-RAF in mouse pulmonary epithelial cells reveals differential tumorigenesis and induction of autophagy leading to tumor regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

In vitro and in vivo anti-tumor activities of anti-EGFR single-chain variable fragment fused with recombinant gelonin toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Autophagy is induced by 3β-O-succinyl-lupeol (LD9-4) in A549 cells via up-regulation of Beclin 1 and down-regulation mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors

21 January 2018

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https://api.crossref.org/works/10.1042%2FCS20120270

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120270

21 January 2018

Identifiers

DOI

10.1042/CS20120270

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10 September 2017

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