Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells (Q39270897)

10 September 2017

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells (English)

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10 September 2017

Michael Groessl

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Paul Dyson

object named as

Paul J Dyson

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3

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author name string

Dirk A Wolters

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1

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PubMed ID

23014849

10 September 2017

Maria Stefanopoulou

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2

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10 September 2017

26 September 2012

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10 September 2017

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10 September 2017

4

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10 September 2017

11

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10 September 2017

1185-1196

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Metal-based antitumour drugs in the post genomic era.

10 September 2017

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

From bench to bedside--preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

A Phase I and pharmacological study with imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a novel ruthenium anticancer agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Bioanalytical and biophysical techniques for the elucidation of the mode of action of metal-based drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cellular processing of platinum anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Lessons from phase III clinical trials on anti-VEGF therapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Proteomic analysis of laser microdissected ovarian cancer tissue with SELDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Up-regulation of mitochondrial antioxidation signals in ovarian cancer cells with aggressive biologic behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Gel-free mass spectrometry-based high throughput proteomics: tools for studying biological response of proteins and proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Advanced MudPIT as a next step toward high proteome coverage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Characterisation of cisplatin binding sites in human serum proteins using hyphenated multidimensional liquid chromatography and ESI tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Characterisation of cisplatin coordination sites in cellular Escherichia coli DNA-binding proteins by combined biphasic liquid chromatography and ESI tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cell response of Escherichia coli to cisplatin-induced stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Evaluation of cell lysis methods for platinum metallomic studies of human malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

A model for random sampling and estimation of relative protein abundance in shotgun proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cisplatin: mode of cytotoxic action and molecular basis of resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

The actin cytoskeleton in cancer cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Targeting mitochondria for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Inhibition of transcription by platinum antitumor compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Increased tight junctional permeability is associated with the development of colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Nature of full-length HMGB1 binding to cisplatin-modified DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cytoskeleton and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

The resurgence of platinum-based cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

DNA-based drug interactions of cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Mitochondria as a critical target of the chemotheraputic agent cisplatin in head and neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

Correlation of Relative Abundance Ratios Derived from Peptide Ion Chromatograms and Spectrum Counting for Quantitative Proteomic Analysis Using Stable Isotope Labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2MT20070H

21 January 2018

Identifiers

DOI

10.1039/C2MT20070H

1 reference

10 September 2017

1 reference

PubMed ID

23014849