MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells (Q39264596)

10 September 2017

MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells (English)

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10 September 2017

hepatocellular carcinoma

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Nathalie Théret

3

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author name string

Jean-Philippe Guégan

1

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10 September 2017

Frédéric Ezan

2

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10 September 2017

Sophie Langouët

4

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10 September 2017

Georges Baffet

5

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10 September 2017

language of work or name

English

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publication date

5 October 2012

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10 September 2017

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10 September 2017

34

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10 September 2017

1

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10 September 2017

38-47

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10 September 2017

Hepatocellular carcinoma

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Future perspectives on the treatment of hepatocellular carcinoma with cisplatin

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Molecular mechanisms of cisplatin resistance

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Anticancer drug targets: cell cycle and checkpoint control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Cellular processing of platinum anticancer drugs

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Requirement for ERK activation in cisplatin-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

A death-promoting role for extracellular signal-regulated kinase

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Bim protein degradation contributes to cisplatin resistance

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Differential regulation and properties of MAPKs

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

The MEK/ERK cascade: from signaling specificity to diverse functions

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Mek2 is dispensable for mouse growth and development

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Distinct functions for ERKs?

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Total ERK1/2 activity regulates cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

The knock-down of ERCC1 but not of XPF causes multinucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Sensitizing glioma cells to cisplatin by abrogating the p53 response with antisense oligonucleotides

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Zinc induces expression of the BH3-only protein PUMA through p53 and ERK pathways in SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Tumour cell survival signalling by the ERK1/2 pathway

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS317

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS317

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10 September 2017

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