Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. (Q39261999)

10 September 2017

Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. (English)

1 reference

10 September 2017

1 reference

Ido Goldstein

1

0 references

Varda Rotter

7

object named as

Varda Rotter

1 reference

10 September 2017

Noa Rivlin

2

1 reference

10 September 2017

Or-yam Shoshana

3

1 reference

10 September 2017

Osnat Ezra

4

1 reference

10 September 2017

Shalom Madar

5

1 reference

10 September 2017

Naomi Goldfinger

6

1 reference

10 September 2017

language of work or name

English

0 references

publication date

10 October 2012

1 reference

10 September 2017

1 reference

10 September 2017

34

1 reference

10 September 2017

190-198

1 reference

10 September 2017

1

1 reference

Clinical importance of the cytochromes P450

10 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The role of nuclear receptors in pharmacokinetic drug-drug interactions in oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Blinded by the Light: The Growing Complexity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Regulation of lipid metabolism by p53 - fighting two villains with one sword.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Metabolic regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Tumor suppressor p53 regulates bile acid homeostasis via small heterodimer partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer-binding protein beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Luminogenic cytochrome P450 assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

p53, a novel regulator of lipid metabolism pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The expanding universe of p53 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The p53MH algorithm and its application in detecting p53-responsive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Direct assessment of promoter activity of human cytochrome p450 genes using optimized transfection in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS318

1 reference

release_2ia7bvm5ezdrfayq3u5awp27fq

10 September 2017

0 references

1 reference