Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A. (Q39251583)

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12 February 2020

title

Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A (English)

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4

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author name string

Andrew J Kale

series ordinal

1

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12 February 2020

Ryan P McGlinchey

series ordinal

2

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Anna Lechner

series ordinal

3

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publication date

26 September 2011

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12 February 2020

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12 February 2020

volume

6

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issue

11

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12 February 2020

page(s)

1257-1264

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The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution

12 February 2020

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1 reference

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Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.

10 September 2017

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Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress

10 September 2017

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Expansion of the mycobacterial "PUPylome"

10 September 2017

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10 September 2017

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Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica

10 September 2017

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Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine

10 September 2017

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Molecular mechanisms of proteasome assembly

10 September 2017

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Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis

10 September 2017

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10 September 2017

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Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants

10 September 2017

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Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

10 September 2017

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20S proteasome and its inhibitors: crystallographic knowledge for drug development

10 September 2017

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Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding

10 September 2017

1 reference

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Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome

10 September 2017

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Protein production by auto-induction in high density shaking cultures

10 September 2017

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The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide

10 September 2017

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Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.

10 September 2017

1 reference

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Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase

10 September 2017

1 reference

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Structure of 20S proteasome from yeast at 2.4 A resolution

10 September 2017

1 reference

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Mining the cinnabaramide biosynthetic pathway to generate novel proteasome inhibitors

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220761

The 20S proteasome of Streptomyces coelicolor.

14 September 2017

1 reference

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Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220761

An endophytic fungus from Nothapodytes foetida that produces camptothecin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220761

Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells

14 September 2017

1 reference

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Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

14 September 2017

1 reference

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Proteome-wide identification of mycobacterial pupylation targets

14 September 2017

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Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors.

15 June 2018

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Point mutation of the proteasome beta5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic lymphoma/leukemia line

21 August 2018

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How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them?

21 August 2018

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Inactivation of the 20S proteasome in Streptomyces lividans and its influence on the production of heterologous proteins.

21 August 2018

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Approval summary for bortezomib for injection in the treatment of multiple myeloma

21 August 2018

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Characterization of the 20S proteasome from the actinomycete Frankia

21 August 2018

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Inactivation of the 20S proteasome in Mycobacterium smegmatis.

21 August 2018

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The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus

21 August 2018

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Cinnabaramides A−G: Analogues of Lactacystin and Salinosporamide from a Terrestrial Streptomycete

21 August 2018

1 reference

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The proteasome/multicatalytic-multifunctional proteinase. In vivo function in the ubiquitin-dependent N-end rule pathway of protein degradation in eukaryotes

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21882868

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Subunit topology of the Rhodococcus proteasome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21882868

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB2002544

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21882868%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

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12 February 2020

1 reference