Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis (Q39244702)

10 September 2017

Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis (English)

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10 September 2017

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viral rna synthesis

13 November 2022

8

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10 September 2017

Eric J Snijder

7

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Yvonne van der Meer

3

object named as

Yvonne van der Meer

1 reference

10 September 2017

Adriaan H de Wilde

1

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10 September 2017

Yanhua Li

2

1 reference

10 September 2017

Grégoire Vuagniaux

4

1 reference

10 September 2017

Robert Lysek

5

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10 September 2017

Ying Fang

6

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10 September 2017

language of work or name

English

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publication date

14 November 2012

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10 September 2017

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10 September 2017

87

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3

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1454-1464

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describes a project that uses

10 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3554155/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Nonstructural protein 2 of porcine reproductive and respiratory syndrome virus inhibits the antiviral function of interferon-stimulated gene 15.

10 September 2017

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Ultrastructural characterization of arterivirus replication structures: reshaping the endoplasmic reticulum to accommodate viral RNA synthesis

10 September 2017

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The dependence of viral RNA replication on co-opted host factors

10 September 2017

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The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

10 September 2017

1 reference

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Cyclosporin A inhibits the replication of diverse coronaviruses

10 September 2017

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Emerging picture of host chaperone and cyclophilin roles in RNA virus replication.

10 September 2017

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DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A

10 September 2017

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The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins

10 September 2017

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Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

10 September 2017

1 reference

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Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A

10 September 2017

1 reference

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Arterivirus Nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs

10 September 2017

1 reference

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Multiple cyclophilins involved in different cellular pathways mediate HCV replication

10 September 2017

1 reference

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Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes

10 September 2017

1 reference

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Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

10 September 2017

1 reference

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Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein

10 September 2017

1 reference

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Critical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication Complex

10 September 2017

1 reference

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The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication

10 September 2017

1 reference

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Host-directed drug targeting of factors hijacked by pathogens

10 September 2017

1 reference

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Immunophilins: for the love of proteins

10 September 2017

1 reference

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Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

10 September 2017

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Nidovirus transcription: how to make sense...?

10 September 2017

1 reference

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Attacking pathogens through their hosts

10 September 2017

1 reference

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Nidovirales: evolving the largest RNA virus genome

10 September 2017

1 reference

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Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

10 September 2017

1 reference

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Isolation of a filterable agent causing arteritis of horses and abortion by mares; its differentiation from the equine abortion (influenza) virus.

10 September 2017

1 reference

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Redistribution of cyclophilin A to viral factories during vaccinia virus infection and its incorporation into mature particles

10 September 2017

1 reference

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Localization of mouse hepatitis virus nonstructural proteins and RNA synthesis indicates a role for late endosomes in viral replication

10 September 2017

1 reference

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Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex

10 September 2017

1 reference

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The mechanism of action of cyclosporin A and FK506

10 September 2017

1 reference

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Structural proteins of equine arteritis virus

10 September 2017

1 reference

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Suppression of feline coronavirus replication in vitro by cyclosporin A.

10 September 2017

1 reference

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A full-length cDNA infectious clone of North American type 1 porcine reproductive and respiratory syndrome virus: expression of green fluorescent protein in the Nsp2 region

10 September 2017

1 reference

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The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Discovery of a potent peptidic cyclophilin A inhibitor Trp-Gly-Pro

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Involvement of cyclophilin B in the replication of Japanese encephalitis virus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Mechanism of resistance of hepatitis C virus replicons to structurally distinct cyclophilin inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

An infectious recombinant equine arteritis virus expressing green fluorescent protein from its replicase gene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

The nucleoprotein is required for efficient coronavirus genome replication.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Specific inhibition of hepatitis C virus replication by cyclosporin A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Serologic response of horses to the structural proteins of equine arteritis virus

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Cyclosporin A inhibits vaccinia virus replication in vitro.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

The in vitro RNA synthesizing activity of the isolated arterivirus replication/transcription complex is dependent on a host factor

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Requirement for cyclophilin A for the replication of vesicular stomatitis virus New Jersey serotype

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Comparison of the effect of FK506 and cyclosporin A on virus production in H9 cells chronically and newly infected by HIV-1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554155

Nucleocapsid Protein Expression Facilitates Coronavirus Replication

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23152531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safety, pharmacokinetics, and antiviral activity of the cyclophilin inhibitor NIM811 alone or in combination with pegylated interferon in HCV-infected patients receiving 14 days of therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23152531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.02078-12

1 reference

release_rvvypic7tvgrlgjscuucvod644

10 September 2017

0 references

1 reference

10 September 2017

PubMed publication ID

23152531

1 reference