Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis. (Q39244593)

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English	Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis.	scientific article

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8 February 2020

Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis (English)

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8 February 2020

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Jarogniew Łuszczki

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8 February 2020

Magdalena Florek-Łuszczki

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8 February 2020

Jarogniew Łuszczki

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object named as

Jarogniew J Luszczki

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10 September 2017

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Magdalena Florek-Łuszczki

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10 September 2017

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1 January 2012

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8 February 2020

Pharmacological Reports

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8 February 2020

723-732

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8 February 2020

Use of anticonvulsants for treatment of neuropathic pain

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The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

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The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain

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Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests

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Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain

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Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin

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Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat

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The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain

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10.1016/S1734-1140(12)70867-8

1 reference

Europe PubMed Central

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8 February 2020

1 reference

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8 February 2020

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