Ruthenium(II) arene PTA (RAPTA) complexes: impact of enantiomerically pure chiral ligands (Q39236976)

10 September 2017

Ruthenium(II) arene PTA (RAPTA) complexes: impact of enantiomerically pure chiral ligands (English)

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10 September 2017

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Paul J Dyson

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author name string

Kelly J Kilpin

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1

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10 September 2017

Shona M Cammack

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2

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10 September 2017

Catherine M Clavel

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3

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10 September 2017

language of work or name

English

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publication date

1 February 2013

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42

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6

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2008-2014

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Organometallic anticancer compounds

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Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy

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Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder.

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Pharmacologically active compounds in the environment and their chirality.

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Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers.

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{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

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Anticancer activity of methyl-substituted oxaliplatin analogs

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Arene ruthenium(II) complexes formed by dehydrogenation of cyclohexadienes with ruthenium(III) trichloride

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1 reference

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Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds

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21 January 2018

Identifiers

DOI

10.1039/C2DT32333H

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10 September 2017

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