Conformational characterization of the charge variants of a human IgG1 monoclonal antibody using H/D exchange mass spectrometry (Q39230268)

10 September 2017

Conformational characterization of the charge variants of a human IgG1 monoclonal antibody using H/D exchange mass spectrometry (English)

1 reference

10 September 2017

1 reference

Liangjie Tang

1

1 reference

10 September 2017

Shanmuuga Sundaram

2

1 reference

10 September 2017

Jingming Zhang

3

1 reference

10 September 2017

Ping Carlson

4

1 reference

10 September 2017

Alice Matathia

5

1 reference

10 September 2017

Babita Parekh

6

1 reference

10 September 2017

Qinwei Zhou

7

1 reference

10 September 2017

Ming-Ching Hsieh

8

1 reference

10 September 2017

6 December 2012

1 reference

10 September 2017

Monoclonal Antibodies

1 reference

10 September 2017

5

1 reference

10 September 2017

1

1 reference

10 September 2017

114-125

1 reference

Hydrogen exchange mass spectrometry: are we out of the quicksand?

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Post-translational modifications differentially affect IgG1 conformation and receptor binding.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

H/D exchange and mass spectrometry-based method for biophysical analysis of multidomain proteins at the domain level

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Analysis of lysine clipping of a humanized Lewis-Y specific IgG antibody and its relation to Fc-mediated effector function

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Accuracy and Precision of a New H/D Exchange- and Mass Spectrometry-Based Technique for Measuring the Thermodynamic Properties of Protein−Peptide Complexes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

A quantitative, high-throughput screen for protein stability

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Primary structure effects on peptide group hydrogen exchange

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Hydrogen exchange and structural dynamics of proteins and nucleic acids

10 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

10 September 2017

https://pubmed.ncbi.nlm.nih.gov/23222183

12 December 2020

inferred from PubMed ID database lookup

Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

C-terminal lysine variants in fully human monoclonal antibodies: investigation of test methods and possible causes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Biophysical characterization of insoluble aggregates of a multi-domain protein: an insight into the role of the various domains

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Protein hydrogen exchange mechanism: local fluctuations

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564876

Glycosylation of human IgG-Fc: influences on structure revealed by differential scanning micro-calorimetry

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23222183

12 December 2020

inferred from PubMed ID database lookup

Fresh from the biologic pipeline-2009

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23222183

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/MABS.22695

1 reference

release_ar32okonuvdsznyjurdawikhxe

10 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ar32okonuvdsznyjurdawikhxe

24 November 2022

mapped directly with Wikidata item

1 reference

10 September 2017

1 reference