Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo (Q39228469)

10 September 2017

Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo (English)

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10 September 2017

Hongchi Jiang

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Xueying Sun

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Xueying Sun

12

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author name string

Zheng Wei

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10 September 2017

Xian Jiang

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10 September 2017

Fengjun Liu

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10 September 2017

Haiquan Qiao

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10 September 2017

Baoguo Zhou

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10 September 2017

Bo Zhai

6

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10 September 2017

Lianfeng Zhang

7

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10 September 2017

Xuwen Zhang

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10 September 2017

Likun Han

9

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10 September 2017

Geoffrey W Krissansen

11

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10 September 2017

language of work or name

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11 December 2012

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10 September 2017

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10 September 2017

34

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10 September 2017

181-192

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10 September 2017

1

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https://scigraph.springernature.com/pub.10.1007/s13277-012-0527-8

10 September 2017

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cites work

Global cancer statistics

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Locoregional treatment of peritoneal carcinomatosis from gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Adjuvant therapy in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Characterization of gene amplification-driven SKP2 overexpression in myxofibrosarcoma: potential implications in tumor progression and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 is a promising therapeutic target in breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 suppresses p53-dependent apoptosis by inhibiting p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Knockdown of S-phase kinase-associated protein-2 expression in MCF-7 inhibits cell growth and enhances the cytotoxic effects of epirubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Overexpression of von Hippel-Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Downregulation of nuclear factor-kappaB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Downregulating hypoxia-inducible factor-2α improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Matrix metalloproteinases and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Complex roles of tissue inhibitors of metalloproteinases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Down-regulation of S-phase kinase associated protein 2 (Skp2) induces apoptosis in oral cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Correlation between Skp2 expression and nodal metastasis in stage I and II oral squamous cell carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

p27Kip1 modulates cell migration through the regulation of RhoA activation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Progress in matrix metalloproteinase research

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Involvement of the SKP2-p27(KIP1) pathway in suppression of cancer cell proliferation by RECK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0527-8

Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27

21 January 2018

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12 December 2020

Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors.

1 reference

12 December 2020

RNA silencing of S-phase kinase-interacting protein 2 inhibits proliferation and centrosome amplification in lung cancer cells

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12 December 2020

High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas

1 reference

12 December 2020

Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation

1 reference

12 December 2020

Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis

1 reference

12 December 2020

10.1007/S13277-012-0527-8

Identifiers

DOI

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10 September 2017

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