Downregulation of Fas activity rescues early onset of diabetes in c-Kit(Wv/+) mice (Q39220534)

10 September 2017

Downregulation of Fas activity rescues early onset of diabetes in c-Kit(Wv/+) mice (English)

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10 September 2017

Zhi-Chao Feng

1

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10 September 2017

Matthew Riopel

2

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10 September 2017

Jinming Li

3

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10 September 2017

Lisa Donnelly

4

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10 September 2017

Rennian Wang

5

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10 September 2017

26 December 2012

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American Journal of Physiology - Endocrinology and Metabolism

10 September 2017

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10 September 2017

304

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10 September 2017

6

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10 September 2017

E557-65

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The biology of stem cell factor and its receptor C-kit

10 September 2017

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https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Differential regulation of Foxo3a target genes in erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Endocrine pancreas plasticity under physiological and pathological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Life and death of the pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Inhibition of Gsk3β activity improves β-cell function in c-KitWv/+ male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Combination of MafA, PDX-1 and NeuroD is a useful tool to efficiently induce insulin-producing surrogate beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Bcl-2 reduced and fas activated by the inhibition of stem cell factor/KIT signaling in murine melanocyte precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

c-Kit in early onset of diabetes: a morphological and functional analysis of pancreatic beta-cells in c-KitW-v mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

A search for tyrosine kinase receptors expressed in the rat embryonic pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

beta-Cell death during progression to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Oocyte growth and follicular development in KIT-deficient Fas-knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Expression of MafA in pancreatic progenitors is detrimental for pancreatic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Stem cell factor prevents Fas-mediated apoptosis of human erythroid precursor cells with Src-family kinase dependency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Expression of Protein Tyrosine Kinases in Islet Cells: Possible Role of the Flk-1 Receptor forβ-Cell Maturation from Duct Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Expression of the receptor tyrosine kinase KIT in mature beta-cells and in the pancreas in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient Wv/Wv mutant mice

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Contribution of Fas to diabetes development

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Control of cell cycle progression by c-Jun is p53 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

The Fas pathway is involved in pancreatic beta cell secretory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Five stages of evolving beta-cell dysfunction during progression to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Role of tyrosine kinase signaling for beta-cell replication and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

c-Kit and stem cell factor regulate PANC-1 cell differentiation into insulin- and glucagon-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

Characterization of c-Kit and nestin expression during islet cell development in the prenatal and postnatal rat pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00453.2012

10.1152/AJPENDO.00453.2012

21 January 2018

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DOI

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10 September 2017

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