Pradigastat disposition in humans: in vivo and in vitro investigations (Q39180625)

9 September 2017

Pradigastat disposition in humans: in vivo and in vitro investigations (English)

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9 September 2017

Alana Upthagrove

1

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9 September 2017

Jin Chen

2

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9 September 2017

Charles D Meyers

3

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9 September 2017

Kenneth Kulmatycki

4

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9 September 2017

Angela Bretz

5

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9 September 2017

Lai Wang

6

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9 September 2017

Lana Peng

7

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9 September 2017

Safet Palamar

8

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9 September 2017

Melissa Lin

9

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9 September 2017

Tapan Majumdar

10

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9 September 2017

Phi Tran

11

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9 September 2017

Heidi J Einolf

12

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9 September 2017

language of work or name

English

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publication date

18 November 2016

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9 September 2017

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9 September 2017

1-13

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Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

9 September 2017

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

Acyl glucuronide drug metabolites: toxicological and analytical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498254.2016.1263405

10.1080/00498254.2016.1263405

21 January 2018

Identifiers

DOI

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9 September 2017

1 reference