New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity (Q39176222)

9 September 2017

New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity (English)

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9 September 2017

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Carole Anne De Carufel

1

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9 September 2017

Phuong Trang Nguyen

2

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9 September 2017

Sabrina Sahnouni

3

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9 September 2017

Steve Bourgault

4

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9 September 2017

1 November 2013

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9 September 2017

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9 September 2017

100

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9 September 2017

6

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9 September 2017

645-655

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Protein misfolding, functional amyloid, and human disease

9 September 2017

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The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

21 January 2018

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Glycosaminoglycans in extracts of cardiac amyloid fibrils from familial amyloid cardiomyopathy of Danish origin related to variant transthyretin Met 111.

21 January 2018

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Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease

21 January 2018

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Sulfated glycosaminoglycans accelerate transthyretin amyloidogenesis by quaternary structural conversion

21 January 2018

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Heparin strongly enhances the formation of beta2-microglobulin amyloid fibrils in the presence of type I collagen

21 January 2018

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Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth

21 January 2018

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Heparin binds 8 kDa gelsolin cross-β-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension

21 January 2018

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Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation

21 January 2018

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Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway

21 January 2018

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Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate.

21 January 2018

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Heparin accelerates gelsolin amyloidogenesis

21 January 2018

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Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

21 January 2018

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Common features between diabetes mellitus and Alzheimer's disease

21 January 2018

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Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

21 January 2018

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Amyloid formation in heterogeneous environments: islet amyloid polypeptide glycosaminoglycan interactions

21 January 2018

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Mechanism of amylin fibrillization enhancement by heparin.

21 January 2018

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Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes

21 January 2018

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Ionic strength effects on amyloid formation by amylin are a complicated interplay among Debye screening, ion selectivity, and Hofmeister effects

21 January 2018

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The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

21 January 2018

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Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

21 January 2018

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The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation

21 January 2018

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A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

21 January 2018

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Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X

21 January 2018

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Animal cell mutants defective in glycosaminoglycan biosynthesis

21 January 2018

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

21 January 2018

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Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

21 January 2018

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A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

21 January 2018

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Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets

21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships

21 January 2018

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Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

21 January 2018

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Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro.

21 January 2018

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Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin.

21 January 2018

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Glycosaminoglycans (GAGs) suppress the toxicity of HypF-N prefibrillar aggregates.

21 January 2018

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Heparin induces harmless fibril formation in amyloidogenic W7FW14F apomyoglobin and amyloid aggregation in wild-type protein in vitro

21 January 2018

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Heparan sulfate mediates amyloid-beta internalization and cytotoxicity

21 January 2018

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Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIP.22243

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9 September 2017

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