A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells. (Q39172701)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

A shift from N-glycolyl- to N-acetyl-sialic acid in the GM3 ganglioside impairs tumor development in mouse lymphocytic leukemia cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

0 references

1 reference

Yuniel Fernandez-Marrero

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Ernesto Moreno

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Ana Victoria Casadesús

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Marilyn Clavell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

José Alberto Gómez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Tays Hernández

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Alejandro López-Requena

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

publication date

2 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

published in

Glycoconjugate Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

687-699

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23547010%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10719-013-9473-y

27 February 2020

exact match

0 references

cites work

Structure, organization, and function of glycosphingolipids in membrane

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Gangliosides in cell recognition and membrane protein regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Gangliosides as components of lipid membrane domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Lipids and membrane lateral organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Gangliosides and the multiscale modulation of membrane structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immunology in the clinic review series; focus on cancer: glycolipids as targets for tumour immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Glycans as targets for therapeutic antitumor antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Multiple changes in sialic acid biology during human evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

The molecular basis for the absence of N-glycolylneuraminic acid in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Metabolism of vertebrate amino sugars with N-glycolyl groups: mechanisms underlying gastrointestinal incorporation of the non-human sialic acid xeno-autoantigen N-glycolylneuraminic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N-glycolylated-glycoconjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Heterophilic NeuGcGM3 ganglioside cancer vaccine in advanced melanoma patients: results of a Phase Ib/IIa study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immunohistochemical Reactivity of the 14F7 Monoclonal Antibody Raised against N-Glycolyl GM3 Ganglioside in Some Benign and Malignant Skin Neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

N-Glycolyl GM3 ganglioside immunoexpression in oral mucosal melanomas of Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Detection of N-glycolyl GM3 ganglioside in neuroectodermal tumors by immunohistochemistry: an attractive vaccine target for aggressive pediatric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immune response to racotumomab in a child with relapsed neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Tissue Reactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Tumors of Neuroectodermal, Mesodermal, and Epithelial Origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Epithelial Malignant Tumors from Digestive System

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

NGcGM3 ganglioside: a privileged target for cancer vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immunotherapy of advanced breast cancer with a heterophilic ganglioside (NeuGcGM3) cancer vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

NGcGM3/VSSP vaccine as treatment for melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Anti-ganglioside antibody-induced tumor cell death by loss of membrane integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Removal of amphipathic epitopes from genetically engineered antibodies: production of modified immunoglobulins with reduced immunogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Lonely killers: effector cell- and complement-independent non-proapoptotic cytotoxic antibodies inducing membrane lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Engineering the binding site of an antibody against N-glycolyl GM3: from functional mapping to novel anti-ganglioside specificities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Characterization of the colorectal antigen IOR-C2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Humanization of Predicted T-Cell Epitopes Reduces the Immunogenicity of Chimeric Antibodies: New Evidence Supporting a Simple Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Chimeric anti-N-glycolyl-ganglioside and its anti-idiotypic MAbs: immunodominance of their variable regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Direct analysis of silica gel extracts from immunostained glycosphingolipids by nanoelectrospray ionization quadrupole time-of-flight mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Solid ionic matrixes for direct tissue analysis and MALDI imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

mMass 3: a cross-platform software environment for precise analysis of mass spectrometric data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

The immunogenicity of L1210 lymphoma clones correlates with their ability to function as antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Lipid Composition of Human Malignant Melanoma Tumors at Various Levels of Malignant Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Immunogenic gangliosides in human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

IgM anti-ganglioside antibodies induced by melanoma cell vaccine correlate with survival of melanoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Glycosphingolipid behaviour in complex membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Direct validation of NGcGM3 ganglioside as a new target for cancer immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

De-N-acetyl GM3 promotes melanoma cell migration and invasion through urokinase plasminogen activator receptor signaling-dependent MMP-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Role of tumor-associated gangliosides in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Differential influence of the tumour-specific non-human sialic acid containing GM3 ganglioside on CD4+CD25- effector and naturally occurring CD4+CD25+ regulatory T cells function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Role of tumour-associated N-glycolylated variant of GM3 ganglioside in cancer progression: effect over CD4 expression on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Gangliosides as immunomodulators

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

21 January 2018

12 December 2020

Immunorecognition of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Some Normal and Malignant Tissues from Genitourinary System

1 reference

https://api.crossref.org/works/10.1007%2FS10719-013-9473-Y

Carbohydrate to carbohydrate interaction in development process and cancer progression

21 January 2018

1 reference

12 December 2020

Clinical evidences of GM3 (NeuGc) ganglioside expression in human breast cancer using the 14F7 monoclonal antibody labelled with (99m)Tc

1 reference

12 December 2020

Neuroblastoma-derived gangliosides inhibit dendritic cell generation and function

1 reference

12 December 2020

Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism

1 reference

12 December 2020

Immunoreactivity of the 14F7 Mab (Raised against N-Glycolyl GM3 Ganglioside) as a Positive Prognostic Factor in Non-Small-Cell Lung Cancer.

1 reference

12 December 2020

In vivo and in vitro anti-tumor effect of 14F7 monoclonal antibody

1 reference

12 December 2020

Aberrant glycosphingolipid expression and membrane organization in tumor cells: consequences on tumor-host interactions

1 reference

12 December 2020

A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors

1 reference

12 December 2020

Antitumor protection by NGcGM3/VSSP vaccine against transfected B16 mouse melanoma cells overexpressing N-glycolylated gangliosides

1 reference

12 December 2020

A novel mechanism of CD4 down-modulation induced by monosialoganglioside GM3. Involvement of serine phosphorylation and protein kinase c delta translocation

1 reference

12 December 2020

Monosialoganglioside GM3 induces CD4 internalization in human peripheral blood T lymphocytes

1 reference

12 December 2020

Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method

1 reference

12 December 2020

An IgG3 monoclonal antibody established after immunization with GM3 lactone: immunochemical specificity and inhibition of melanoma cell growth in vitro and in vivo.

1 reference

12 December 2020

Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data

1 reference

12 December 2020

Detection and characterization of N-glycolyated gangliosides in Wilms tumor by immunohistochemistry

1 reference

12 December 2020

Molecular cloning of a human monoclonal antibody reactive to ganglioside GM3 antigen on human cancers.

1 reference

12 December 2020

Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma

1 reference

12 December 2020

Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer

1 reference

12 December 2020

Clonal variation in tumorigenicity of L1210 lymphoma cells: nontumorigenic variants with an enhanced expression of tumor-associated antigen and Ia antigens

1 reference

12 December 2020

Immunogenicity and safety of a NeuGcGM3 based cancer vaccine: Results from a controlled study in metastatic breast cancer patients

1 reference

12 December 2020

Generation of a murine monoclonal antibody specific for N-glycolylneuraminic acid-containing gangliosides that also recognizes sulfated glycolipids

1 reference

12 December 2020

Gangliosides of human melanoma

1 reference

12 December 2020

Ganglioside G(M3) overexpression induces apoptosis and reduces malignant potential in murine bladder cancer

1 reference

12 December 2020

Gangliosides expressed in human breast cancer

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

1 reference

12 December 2020

Glycotherapy for cancer: remodeling of ganglioside pattern as an effective approach for cancer therapy

1 reference

12 December 2020