ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway (Q39159149)

9 September 2017

ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway (English)

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9 September 2017

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hepatocellular carcinoma

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Xiang-Jun Wang

1

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9 September 2017

Chang-Wei Feng

series ordinal

2

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9 September 2017

Min Li

series ordinal

3

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9 September 2017

28 April 2013

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Molecular and Cellular Biochemistry

9 September 2017

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9 September 2017

380

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9 September 2017

1-2

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9 September 2017

57-66

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https://scigraph.springernature.com/pub.10.1007/s11010-013-1657-z

9 September 2017

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cites work

Tumor hypoxia: a target for selective cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Identification and function of hypoxia-response genes in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Tumor necrosis factor-alpha converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

ADAMs (a disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

ADAM17 mRNA expression and pathological features of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Up-regulated expression of ADAM17 in human colon carcinoma: co-expression with EGFR in neoplastic and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Tumor necrosis factor α-converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Tobacco Smoke-induced Lung Cell Proliferation Mediated by Tumor Necrosis Factor α-converting Enzyme and Amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

TACE is required for the activation of the EGFR by TGF-alpha in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Chemotherapy-induced activation of ADAM-17: a novel mechanism of drug resistance in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Inhibition of TACE activity enhances the susceptibility of myeloma cells to TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

TACE/ADAM17 is involved in germ cell apoptosis during rat spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

ADAM17 as a therapeutic target in multiple diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

ADAM17 promotes glioma cell malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Cross-domain inhibition of TACE ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

MRI of the tumor microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

EMT: a new vision of hypoxia promoting cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

VEGF, HIF-1α expression and MVD as an angiogenic network in familial breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-013-1657-Z

Hypoxia-inducible factor mediates hypoxic and tumor necrosis factor alpha-induced increases in tumor necrosis factor-alpha converting enzyme/ADAM17 expression by synovial cells

21 January 2018

1 reference

12 December 2020

Drug evaluation: apratastat, a novel TACE/MMP inhibitor for rheumatoid arthritis

1 reference

12 December 2020

ADAM17 regulates prostate cancer cell proliferation through mediating cell cycle progression by EGFR/PI3K/AKT pathway

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12 December 2020

Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer

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12 December 2020

Hypoxia-Inducible Factor-1 (HIF-1)

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12 December 2020

Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma

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12 December 2020

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

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12 December 2020

10.1007/S11010-013-1657-Z

Identifiers

DOI

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release_wyuoba44pjgo3fivngj6smfpuq

9 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/wyuoba44pjgo3fivngj6smfpuq

24 November 2022

mapped directly with Wikidata item

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