The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. (Q39130461)

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16 February 2020

review article

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title

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014 (English)

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16 February 2020

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3

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Carsten Denkert

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Giuseppe Floris

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Sylvia Adams

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Sherene Loi

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author name string

R Salgado

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N Sirtaine

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F Klauschen

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G Pruneri

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S Wienert

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G Van den Eynden

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F L Baehner

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E A Perez

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E A Thompson

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W F Symmans

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A L Richardson

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J Brock

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C Criscitiello

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H Bailey

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M Ignatiadis

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J Sparano

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Z Kos

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T Nielsen

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D L Rimm

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K H Allison

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J S Reis-Filho

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C Sotiriou

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G Viale

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K Willard-Gallo

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International TILs Working Group 2014

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F Penault-Llorca

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S Loibl

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publication date

11 September 2014

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16 February 2020

volume

26

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page(s)

259-271

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issue

2

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Objective measurement and clinical significance of TILs in non-small cell lung cancer

16 February 2020

cites work

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12 December 2020

Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients

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Association between CD8+ T-cell infiltration and breast cancer survival in 12,439 patients

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Genetic and phenotypic diversity in breast tumor metastases

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Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

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Tumor-infiltrating lymphocytes predict response to neoadjuvant chemotherapy in patients with breast carcinoma.

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The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures

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Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer

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Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

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12 December 2020

Multiplexed quantitative analysis of CD3, CD8, and CD20 predicts response to neoadjuvant chemotherapy in breast cancer

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Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

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Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

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Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer.

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Use of archived specimens in evaluation of prognostic and predictive biomarkers

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Radiation therapy to convert the tumor into an in situ vaccine

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The blockade of immune checkpoints in cancer immunotherapy

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Prognostic significance of FOXP3+ tumor-infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration

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Innate and adaptive immune cells in the tumor microenvironment

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

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In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas

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12 December 2020

Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer

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Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer

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Cancer and inflammation: promise for biologic therapy.

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Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy

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A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin C as a Compatible Prognostic Marker in Human Solid Tumors

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Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum

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12 December 2020

In situ quantitation of inflammatory mononuclear cells in ductal infiltrating breast carcinoma. Relation to prognostic parameters

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Multicentric neoadjuvant phase II study of panitumumab combined with an anthracycline/taxane-based chemotherapy in operable triple-negative breast cancer: identification of biologically defined signatures predicting treatment impact

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Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

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CD4⁺ follicular helper T cell infiltration predicts breast cancer survival

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Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial

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Leukocytes in mammary development and cancer

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12 December 2020

CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer

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12 December 2020

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

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12 December 2020

Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98

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12 December 2020

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

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12 December 2020

Correlation between Th17 cells and tumor microenvironment

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Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199.

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CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

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Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer.

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12 December 2020

New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape

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Chemotherapy and radiotherapy: cryptic anticancer vaccines

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12 December 2020

The prognostic significance of B lymphocytes in invasive carcinoma of the breast.

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12 December 2020

Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study

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12 December 2020

Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer--a substudy of the neoadjuvant GeparQuinto trial

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12 December 2020

Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients

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12 December 2020

Identifiers

DOI

10.1093/ANNONC/MDU450

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16 February 2020

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16 February 2020

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