Antiepileptics topiramate and levetiracetam alleviate behavioral deficits and reduce neuropathology in APPswe/PS1dE9 transgenic mice (Q39119968)

9 September 2017

Antiepileptics topiramate and levetiracetam alleviate behavioral deficits and reduce neuropathology in APPswe/PS1dE9 transgenic mice (English)

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9 September 2017

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4

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14 May 2020

author name string

Jian-Quan Shi

1

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14 May 2020

Bian-Rong Wang

2

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14 May 2020

You-Yong Tian

3

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14 May 2020

Li Gao

5

1 reference

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14 May 2020

Shu-Li Zhao

6

1 reference

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14 May 2020

Teng Jiang

7

1 reference

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14 May 2020

Hong-Guang Xie

8

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14 May 2020

Ying-Dong Zhang

9

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14 May 2020

publication date

27 July 2013

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CNS Neuroscience & Therapeutics

9 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493595&resulttype=core&format=json

14 May 2020

volume

19

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14 May 2020

page(s)

871-881

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14 May 2020

issue

11

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describes a project that uses

14 May 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

1 reference

A hundred years of Alzheimer's disease research

21 January 2018

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Amyloid precursor protein processing and Alzheimer's disease

21 January 2018

1 reference

Biochemistry and cell biology of tau protein in neurofibrillary degeneration

21 January 2018

1 reference

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

'Clinical trials in Alzheimer's disease': immunotherapy approaches

21 January 2018

1 reference

Seizures and myoclonus in patients with Alzheimer's disease.

21 January 2018

1 reference

Dementia and adult-onset unprovoked seizures.

21 January 2018

1 reference

Incidence and predictors of seizures in patients with Alzheimer's disease

21 January 2018

1 reference

Epilepsy and cognitive impairments in Alzheimer disease

21 January 2018

1 reference

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

21 January 2018

1 reference

Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.

21 January 2018

1 reference

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.

21 January 2018

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Neuronal activity regulates the regional vulnerability to amyloid-β deposition

21 January 2018

1 reference

Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment

21 January 2018

1 reference

Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

21 January 2018

1 reference

Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

21 January 2018

1 reference

The activity of antiepileptic drugs as histone deacetylase inhibitors

21 January 2018

1 reference

The mechanism of neuroprotection by topiramate in an animal model of epilepsy.

21 January 2018

1 reference

Levetiracetam in brain ischemia: clinical implications in neuroprotection and prevention of post-stroke epilepsy

21 January 2018

1 reference

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

21 January 2018

1 reference

Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications

21 January 2018

1 reference

Altered histone acetylation is associated with age-dependent memory impairment in mice.

21 January 2018

1 reference

An epigenetic blockade of cognitive functions in the neurodegenerating brain

21 January 2018

1 reference

Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder.

21 January 2018

1 reference

Valproic acid increases white matter repair and neurogenesis after stroke

21 January 2018

1 reference

Neuroprotective effects of valproic acid following transient global ischemia in rats.

21 January 2018

1 reference

Valproic acid ameliorates inflammation in experimental autoimmune encephalomyelitis rats

21 January 2018

1 reference

The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y.

21 January 2018

1 reference

Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels

21 January 2018

1 reference

Valproic acid as a promising agent to combat Alzheimer's disease

21 January 2018

1 reference

Chronic divalproex sodium use and brain atrophy in Alzheimer disease

21 January 2018

1 reference

Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease.

21 January 2018

1 reference

Adverse effects of antiepileptic drugs

21 January 2018

1 reference

Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats.

21 January 2018

1 reference

Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury

21 January 2018

1 reference

Neuroprotective properties of the novel antiepileptic drug levetiracetam in the rat middle cerebral artery occlusion model of focal cerebral ischemia

21 January 2018

1 reference

Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus.

21 January 2018

1 reference

Roles of AMP-activated protein kinase in Alzheimer's disease.

21 January 2018

1 reference

The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

21 January 2018

1 reference

Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis

21 January 2018

1 reference

AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

21 January 2018

1 reference

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.

21 January 2018

1 reference

Autophagy failure in Alzheimer's disease--locating the primary defect

21 January 2018

1 reference

Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease.

21 January 2018

1 reference

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

21 January 2018

1 reference

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

21 January 2018

1 reference

Topiramate dose effects on cognition: a randomized double-blind study

21 January 2018

1 reference

Cognitive effects of topiramate in migraine patients aged 12 through 17 years

21 January 2018

1 reference

Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent.

21 January 2018

1 reference

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

12 December 2020

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier

1 reference

12 December 2020

Autophagy dysfunction in Alzheimer's disease

1 reference

12 December 2020

Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains

1 reference

12 December 2020

Impairments in brain-to-blood transport of amyloid-β and reabsorption of cerebrospinal fluid in an animal model of Alzheimer's disease are reversed by antisense directed against amyloid-β protein precursor.

1 reference

12 December 2020

Topiramate promotes neurological recovery in a new model of traumatic brain injury in rats

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12 December 2020

Neuroprotective effect of levetiracetam on hippocampal sclerosis-like change in spontaneously epileptic rats

1 reference

12 December 2020

Down-regulation of amyloid-β through AMPK activation by inhibitors of GSK-3β in SH-SY5Y and SH-SY5Y-AβPP695 cells

1 reference

12 December 2020

Anti-inflammatory effects of levetiracetam in experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.1111/CNS.12144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493595&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493595&resulttype=core&format=json

14 May 2020

1 reference