Glucose regulates hypothalamic long-chain fatty acid metabolism via AMP-activated kinase (AMPK) in neurons and astrocytes (Q39062476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240094%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Glucose regulates hypothalamic long-chain fatty acid metabolism via AMP-activated kinase (AMPK) in neurons and astrocytes (English)

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1 March 2020

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1 reference

6

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1 March 2020

author name string

Bouchra Taïb

1

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1 March 2020

Khalil Bouyakdan

2

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1 March 2020

Cécile Hryhorczuk

3

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1 March 2020

Demetra Rodaros

4

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1 March 2020

Stephanie Fulton

5

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1 March 2020

language of work or name

English

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publication date

15 November 2013

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Journal of Biological Chemistry

1 March 2020

published in

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1 March 2020

volume

288

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1 March 2020

issue

52

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1 March 2020

page(s)

37216-37229

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Hypothalamic malonyl-CoA and the control of food intake

1 March 2020

cites work

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9 September 2017

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Consumption of a high-fat diet, but not regular endurance exercise training, regulates hypothalamic lipid accumulation in mice.

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9 September 2017

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9 September 2017

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Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents

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AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons

9 September 2017

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Characteristics and mechanisms of hypothalamic neuronal fatty acid sensing

9 September 2017

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Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

9 September 2017

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CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity

9 September 2017

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Regulation of hypothalamic malonyl-CoA by central glucose and leptin.

9 September 2017

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Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia

9 September 2017

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Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

9 September 2017

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AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

9 September 2017

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Effects of glucose and insulin on glucokinase activity in rat hypothalamus

9 September 2017

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Astroglial heterogeneity closely reflects the neuronal-defined anatomy of the adult murine CNS

9 September 2017

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Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia

9 September 2017

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Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms?

9 September 2017

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Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

9 September 2017

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9 September 2017

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activation

9 September 2017

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Regulation of brain insulin mRNA by glucose and glucagon-like peptide 1.

14 September 2017

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Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels

14 September 2017

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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

17 June 2018

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A role for hypothalamic malonyl-CoA in the control of food intake

17 June 2018

1 reference

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Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin

17 June 2018

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The AMP-activated protein kinase is involved in the regulation of ketone body production by astrocytes.

17 June 2018

1 reference

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Palmitate incorporation into different brain regions in the awake rat.

17 June 2018

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Level of satiety: fatty acid and glucose metabolism in three brain sites associated with feeding

17 June 2018

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Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture.

17 June 2018

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Influence of fatty acid oxidation in lateral hypothalamus on food intake and body composition.

17 June 2018

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Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei.

17 June 2018

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Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism.

21 August 2018

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Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

21 August 2018

1 reference

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Modulation of astrocytic metabolic phenotype by proinflammatory cytokines

21 August 2018

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Localization and effect of ectopic expression of CPT1c in CNS feeding centers.

21 August 2018

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Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake.

21 August 2018

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Molecular disruption of hypothalamic nutrient sensing induces obesity

21 August 2018

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Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels

21 August 2018

1 reference

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Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats

21 August 2018

1 reference

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Regulation of blood glucose by hypothalamic pyruvate metabolism

21 August 2018

1 reference

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Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

21 August 2018

1 reference

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Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats.

21 August 2018

1 reference

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A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus

21 August 2018

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Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

21 August 2018

1 reference

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Hypothalamic responses to long-chain fatty acids are nutritionally regulated

21 August 2018

1 reference

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Acute intracarotid glucose injection towards the brain induces specific c-fos activation in hypothalamic nuclei: involvement of astrocytes in cerebral glucose-sensing in rats.

21 August 2018

1 reference

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A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli

21 August 2018

1 reference

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Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

21 August 2018

1 reference

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Central administration of oleic acid inhibits glucose production and food intake

21 August 2018

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21 August 2018

Identifiers

DOI

10.1074/JBC.M113.506238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240094%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240094%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference