Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake (Q39051498)

8 September 2017

Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake (English)

1 reference

8 September 2017

4

1 reference

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1 June 2020

John D. Horowitz

6

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1 June 2020

author name string

Nigel E Drury

1

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1 June 2020

Giovanni Licari

2

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1 June 2020

Cher-Rin Chong

3

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1 June 2020

Michael P Frenneaux

5

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1 June 2020

Domenico Pagano

7

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1 June 2020

Benedetta C Sallustio

8

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1 June 2020

language of work or name

English

0 references

publication date

1 May 2014

1 reference

British Journal of Clinical Pharmacology

8 September 2017

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1 June 2020

volume

77

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1 June 2020

issue

5

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1 June 2020

page(s)

789-795

1 reference

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Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography.

1 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Efficacy and safety of perhexiline maleate in refractory angina. A double-blind placebo-controlled clinical trial of a novel antianginal agent

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Myocardial uptake of drugs and clinical effects

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Relationship between plasma perhexiline concentration and symptomatic status during short-term perhexiline therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Short-term myocardial uptake of lidocaine and mexiletine in patients with ischemic heart disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Accumulation of drugs by resting or beating cardiac tissue

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Effects of aging, renal dysfunction, left ventricular systolic impairment, and weight on steady state pharmacokinetics of perhexiline.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state dose

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

A model of the first pass passage of drugs from i.v. injection site to the heart--parameter estimates for lignocaine in the sheep.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4004399

Procainamide delivery to ischemic canine myocardium following rapid intravenous administration

21 August 2018

1 reference

12 December 2020

Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics

1 reference

12 December 2020

Acute myocardial uptake of digoxin in humans: correlation with hemodynamic and electrocardiographic effects

1 reference

12 December 2020

Inhibition by perhexiline of oxidative phosphorylation and the beta-oxidation of fatty acids: possible role in pseudoalcoholic liver lesions

1 reference

12 December 2020

Influence of myocardial mechanical activity and coronary blood flow on myocardial digoxin uptake

1 reference

12 December 2020

Identifiers

DOI

10.1111/BCP.12254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117487%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117487%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

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