C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis (Q39025727)

8 September 2017

C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis (English)

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8 September 2017

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Bo Pan

1

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8 September 2017

Lifeng Yang

2

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8 September 2017

Jin Wang

3

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8 September 2017

Yunsheng Wang

4

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8 September 2017

Jihong Wang

5

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8 September 2017

Xiangmei Zhou

6

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8 September 2017

Xiaomin Yin

7

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8 September 2017

Zhongqiu Zhang

8

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8 September 2017

Deming Zhao

9

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8 September 2017

8 February 2014

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8 September 2017

Molecular Neurobiology

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8 September 2017

49

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8 September 2017

2

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8 September 2017

1102-1116

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https://scigraph.springernature.com/pub.10.1007/s12035-014-8646-4

8 September 2017

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Regulation of chaperone effects on a yeast prion by cochaperone Sgt2.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Prion proteins leading to neurodegeneration.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Prion protein functions and dysfunction in prion diseases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Molecular biology of prion diseases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126).

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Neurotoxicity of a prion protein fragment.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

PrP(106-126) does not interact with membranes under physiological conditions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Neuronal apoptosis in Creutzfeldt-Jakob disease.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

c-Abl tyrosine kinase selectively regulates p73 nuclear matrix association.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The effects of c-Abl mutation on developing B cell differentiation and survival

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Culturing hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Cellular prion protein (PrPC) of the neuron cell transformed to a PK-resistant protein under oxidative stress, comprising main mitochondrial damage in prion diseases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Inhibition of phagocytosis reduced the classical activation of BV2 microglia induced by amyloidogenic fragments of beta-amyloid and prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

c-Abl in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Two distinct phosphorylation pathways have additive effects on Abl family kinase activation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Targeting the regulatory machinery of BIM for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

BCL2A1: the underdog in the BCL2 family

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Cooperative roles of c-Abl and Cdk5 in regulation of p53 in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Regulation of neuronal cell death by MST1-FOXO1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The PKCdelta -Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Microglia and prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Oxidative stress caused by blocking of mitochondrial complex I H(+) pumping as a link in aging/disease vicious cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Autophagy and its possible roles in nervous system diseases, damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Autophagy in health and disease: a double-edged sword

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Autophagy: molecular mechanisms, physiological functions and relevance in human pathology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Maturation of autophagic vacuoles in Mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Neuronal autophagy and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die--that is the question

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8646-4

Neuronal apoptosis in fatal familial insomnia

21 January 2018

1 reference

12 December 2020

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?

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12 December 2020

c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines

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12 December 2020

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

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12 December 2020

Death by Abl: a matter of location

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12 December 2020

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12 December 2020

Detection of apoptosis induced DNA cleavage in scrapie-infected sheep brain

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12 December 2020

Neuronal loss and apoptosis in experimental Creutzfeldt-Jakob disease in mice

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12 December 2020

The 139H scrapie agent produces hypothalamic neurotoxicity and pancreatic islet histopathology: electron microscopic studies.

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12 December 2020

Autophagy: a barrier or an adaptive response to cancer.

1 reference

12 December 2020

Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126

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12 December 2020

Prion peptide 106-126 modulates the aggregation of cellular prion protein and induces the synthesis of potentially neurotoxic transmembrane PrP

1 reference

12 December 2020

Neuronal c-Abl overexpression leads to neuronal loss and neuroinflammation in the mouse forebrain.

1 reference

12 December 2020

Oxidative stress and the prion protein in transmissible spongiform encephalopathies

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12 December 2020

In vivo cytotoxicity of the prion protein fragment 106-126

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12 December 2020

Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics

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12 December 2020

10.1007/S12035-014-8646-4

Identifiers

DOI

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8 September 2017

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