Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization (Q39016000)

8 September 2017

Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization (English)

1 reference

High mobility group box 1

8 September 2017

0 references

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Dora Brites

series ordinal

4

1 reference

8 September 2017

Carolina Cunha

1

0 references

Cátia Gomes

object named as

Cátia Gomes

series ordinal

2

0 references

Ana R. Vaz

object named as

Ana Rita Vaz

series ordinal

3

0 references

publication date

21 December 2016

1 reference

Mediators of Inflammation

8 September 2017

1 reference

8 September 2017

2016

1 reference

8 September 2017

6986175

1 reference

Creative Commons Attribution 4.0 International

8 September 2017

start time

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5209629/fullTextXML

inferred from PubMed Central ID database lookup

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Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

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Inflamma-miRs in Aging and Breast Cancer: Are They Reliable Players?

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NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

9 September 2017

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Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

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Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

9 September 2017

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Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

9 September 2017

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Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels

9 September 2017

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Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells

9 September 2017

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Microglia and inflammation: conspiracy, controversy or control?

9 September 2017

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Microglia change from a reactive to an age-like phenotype with the time in culture

9 September 2017

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Microglia centered pathogenesis in ALS: insights in cell interconnectivity

9 September 2017

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MicroRNAs: new regulators of Toll-like receptor signalling pathways

9 September 2017

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Nitric oxide/cyclic GMP signaling regulates motility of a microglial cell line and primary microglia in vitro

9 September 2017

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Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

9 September 2017

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Inflammasomes in the CNS.

9 September 2017

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IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation

9 September 2017

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Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

9 September 2017

1 reference

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Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia

9 September 2017

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MicroRNAs as novel regulators of neuroinflammation

9 September 2017

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The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

9 September 2017

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Involvement of microRNA in microglia-mediated immune response

9 September 2017

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Regulation of HMGB1 release by inflammasomes

9 September 2017

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Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

9 September 2017

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Essential role of MFG-E8 for phagocytic properties of microglial cells

9 September 2017

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Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

9 September 2017

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MicroRNA-124 as a novel treatment for persistent hyperalgesia

9 September 2017

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MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

9 September 2017

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MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state

9 September 2017

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Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia

9 September 2017

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Dynamic motility of microglia: purinergic modulation of microglial movement in the normal and pathological brain

9 September 2017

1 reference

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Outbred ICR/CD1 mice display more severe neuroinflammation mediated by microglial TLR4/CD14 activation than inbred C57Bl/6 mice

9 September 2017

1 reference

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A trio of microRNAs that control Toll-like receptor signalling

9 September 2017

1 reference

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HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.

9 September 2017

1 reference

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MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

9 September 2017

1 reference

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The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective

9 September 2017

1 reference

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Resveratrol differentially modulates inflammatory responses of microglia and astrocytes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Export of microRNAs and microRNA-protective protein by mammalian cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Microglia: biology and pathology

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

miR-146a is critical for endotoxin-induced tolerance: IMPLICATION IN INNATE IMMUNITY.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Adenosine A(2A) receptor mediates microglial process retraction

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Milk fat globule epidermal growth factor-factor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Microglial clearance function in health and disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Control of microglial neurotoxicity by the fractalkine receptor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

ATP mediates rapid microglial response to local brain injury in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Microglia: phagocyte and glia cell.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Identification of a factor that links apoptotic cells to phagocytes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Functional expression of the fractalkine (CX3C) receptor and its regulation by lipopolysaccharide in rat microglia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

9 September 2017

Reactive microgliosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

N9 microglial cells polarized by LPS and IL4 show differential responses to secondary environmental stimuli

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

LPS-induced iNOS expression in N9 microglial cells is suppressed by geniposide via ERK, p38 and nuclear factor-κB signaling pathways

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

LPS induces HMGB1 relocation and release by activating the NF-κB-CBP signal transduction pathway in the murine macrophage-like cell line RAW264.7.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Sildenafil attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-κB signaling pathways in N9 microglia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Inflammasome-induced IL-1β secretion in microglia is characterized by delayed kinetics and is only partially dependent on inflammatory caspases.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Induction and subcellular localization of high-mobility group box-1 (HMGB1) in the postischemic rat brain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Monokine production by microglial cell clones

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Microglia display modest phagocytic capacity for extracellular tau oligomers

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Dynamics of neuron-glia interplay upon exposure to unconjugated bilirubin

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Neutrophil chemotaxis and local expression of interleukin-10 in the tolerance of endotoxin-induced uveitis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Decreased expression of the fractalkine receptor CX3CR1 on circulating monocytes as new feature of sepsis-induced immunosuppression.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Early activation, motility, and homing of neonatal microglia to injured neurons does not require protein synthesis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Innate immune response gene expression profiles of N9 microglia are pathogen-type specific

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Minocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusion

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

Comparison of polarization properties of human adult microglia and blood-derived macrophages

21 August 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

4 November 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5209629

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

2 December 2018

1 reference

12 December 2020

TLR2 signaling directs NO-dependent MMP-9 induction in mouse microglia

1 reference

12 December 2020

TGFβ1 increases microglia-mediated engulfment of apoptotic cells via upregulation of the milk fat globule-EGF factor 8

1 reference

12 December 2020

Antiinflammatory effects of estrogen on microglial activation

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12 December 2020

Identifiers

DOI

10.1155/2016/6986175

1 reference

8 September 2017

1 reference

8 September 2017

1 reference

PMCID

5209629