Nilotinib enhances the efficacy of conventional chemotherapeutic drugs in CD34⁺CD38⁻ stem cells and ABC transporter overexpressing leukemia cells (Q39013427)

From Wikidata

Jump to navigation Jump to search

scientific article published on 19 March 2014

Language	Label	Description	Also known as
English	Nilotinib enhances the efficacy of conventional chemotherapeutic drugs in CD34⁺CD38⁻ stem cells and ABC transporter overexpressing leukemia cells	scientific article published on 19 March 2014

Statements

scholarly article

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Nilotinib enhances the efficacy of conventional chemotherapeutic drugs in CD34⁺CD38⁻ stem cells and ABC transporter overexpressing leukemia cells (English)

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Fang Wang

1

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Xiao-Kun Wang

2

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Cheng-Jun Shi

3

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Hui Zhang

4

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Ya-Peng Hu

5

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Yi-Fan Chen

6

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

Li-Wu Fu

7

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

language of work or name

0 references

publication date

19 March 2014

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

19

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

3

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

3356-3375

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

copyright license

Creative Commons Attribution 4.0 International

19 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

ABC transporters: the power to change

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The role of MDR-related proteins in the prognosis of adult acute myeloid leukaemia (AML) with normal karyotype.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Prognostic significance of multidrug resistance gene 1 (MDR1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) mRNA expression in acute leukemia

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Expression of MRP1 gene in acute leukemia

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Cancer stem cells in tumor heterogeneity.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The cancer stem cell: premises, promises and challenges

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Leukemia stem cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The clinical and therapeutic implications of cancer stem cell biology

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Tumour stem cells and drug resistance

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

ATP-binding-cassette transporters in hematopoietic stem cells and their utility as therapeutical targets in acute and chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Evidence that a cell-type-specific efflux pump regulates cell differentiation in Dictyostelium.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Drug resistance: still a daunting challenge to the successful treatment of AML.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Lapatinib and erlotinib are potent reversal agents for MRP7 (ABCC10)-mediated multidrug resistance

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Apatinib (YN968D1) enhances the efficacy of conventional chemotherapeutical drugs in side population cells and ABCB1-overexpressing leukemia cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna (nilotinib): evidence for transport of Tasigna and its fluorescent derivative by ABC drug transporters

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19033356

21 January 2018

The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential expression of a high number of ATP binding cassette transporters in both normal and leukemic CD34+CD38- cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic value of P-glycoprotein (ABCB) and breast cancer resistance protein (ABCG2) in adults with de novo acute myeloid leukemia with normal karyotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axitinib targeted cancer stemlike cells to enhance efficacy of chemotherapeutic drugs via inhibiting the drug transport function of ABCG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primitive human hematopoietic cells displaying differential efflux of the rhodamine 123 dye have distinct biological activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A low but functionally significant MDR1 expression protects primitive haemopoietic progenitor cells from anthracycline toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24651611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES19033356

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

1 reference

Europe PubMed Central

1 July 2019

http://europepmc.org/abstract/PMC/6270868

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39013427&oldid=1862261843"