Loss of Dlg5 expression promotes the migration and invasion of prostate cancer cells via Girdin phosphorylation (Q39012294)

8 September 2017

Loss of Dlg5 expression promotes the migration and invasion of prostate cancer cells via Girdin phosphorylation (English)

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8 September 2017

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4

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11 June 2020

Noriyuki Kioka

5

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11 June 2020

author name string

L Tomiyama

1

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11 June 2020

T Sezaki

2

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11 June 2020

M Matsuo

3

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11 June 2020

language of work or name

English

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publication date

24 March 2014

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8 September 2017

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11 June 2020

volume

34

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11 June 2020

page(s)

1141-1149

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11 June 2020

issue

9

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https://scigraph.springernature.com/pub.10.1038/onc.2014.31

11 June 2020

exact match

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cites work

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Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55

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The cloning, genomic organization and tissue expression profile of the human DLG5 gene

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Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact

21 January 2018

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Discs large 5 is required for polarization of citron kinase in mitotic neural precursors

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Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice

21 January 2018

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A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration

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Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis

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On the role of PDZ domain-encoding genes in Drosophila border cell migration.

21 January 2018

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Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells

21 January 2018

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Dlg5 interacts with the TGF-β receptor and promotes its degradation

21 January 2018

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Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

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Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection

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Integrins in prostate cancer progression

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Targeting constitutively activated β1 integrins inhibits prostate cancer metastasis

21 January 2018

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Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

21 January 2018

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Akt/PKB regulates actin organization and cell motility via Girdin/APE

21 January 2018

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GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling

21 January 2018

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An actin-binding protein Girdin regulates the motility of breast cancer cells

21 January 2018

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Activation of Galphai3 triggers cell migration via regulation of GIV.

21 January 2018

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Perturbations of the AKT signaling pathway in human cancer

21 January 2018

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Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer.

21 January 2018

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The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells

21 January 2018

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

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Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

21 January 2018

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The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury.

21 January 2018

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Girdin maintains the stemness of glioblastoma stem cells.

21 January 2018

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Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.

21 January 2018

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A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

21 January 2018

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Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer

21 January 2018

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A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate

21 January 2018

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Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

21 January 2018

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WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions.

21 January 2018

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Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin

21 January 2018

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Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases

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Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24662825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662825%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference