Glutathione peroxidase 4: a new player in neurodegeneration? (Q38989886)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

review article

1 reference

title

Glutathione peroxidase 4: a new player in neurodegeneration? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Ashley I. Bush

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Blaine R Roberts

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

B R Cardoso

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

language of work or name

English

0 references

publication date

25 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

328-335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/mp.2016.196

26 March 2020

exact match

0 references

cites work

Characterization of mammalian selenoproteomes.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

21 January 2018

Glutathione peroxidases

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Selenoproteins and the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Mapping of the N-linked glycoproteome of human spermatozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Selenoproteins in nervous system development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Ferroptosis: an iron-dependent form of nonapoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The catalytic site of glutathione peroxidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Addition of docosahexaenoic acid, but not arachidonic acid, activates glutathione and thioredoxin antioxidant systems in murine hippocampal HT22 cells: potential implications in neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Brain glutathione levels--a novel biomarker for mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Mitochondrial glutathione peroxidase 4 disruption causes male infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Differential splicing of the phospholipid hydroperoxide glutathione peroxidase gene in diploid and haploid male germ cells in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The nuclear form of glutathione peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Zonisamide suppresses endoplasmic reticulum stress-induced neuronal cell damage in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Markers of oxidative stress in plasma and saliva in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Ischemia modified albumin is an indicator of oxidative stress in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Oxidative stress biomarkers in sporadic ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: specific induction of enzyme expression in reactive astrocytes following brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Interaction of aldehydes derived from lipid peroxidation and membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The Role of Oxidative Stress in Neurodegenerative Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The role of metallobiology and amyloid-β peptides in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Membrane redox state and apoptosis: death by peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Oxidatively modified proteins in aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Selenium, selenoproteins and neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Selenocysteine robustness versus cysteine versatility: a hypothesis on the evolution of the moonlighting behaviour of peroxiredoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Peroxynitrite reductase activity of selenoprotein glutathione peroxidase: a computational study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Characterization and structural analysis of human selenium-dependent glutathione peroxidase 4 mutant expressed in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Why is DsbA such an oxidizing disulfide catalyst?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild-type selenoenzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Methamphetamine decreases levels of glutathione peroxidases 1 and 4 in SH-SY5Y neuronal cells: protective effects of selenium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Selenium supplementation shows protective effects against patulin-induced brain damage in mice via increases in GSH-related enzyme activity and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

A comparative study on effect of dietary selenium and vitamin E on some antioxidant enzyme activities of liver and brain tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Minireview: pH and synaptic transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Homeostasis of metals in the progression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Effects of Brazil nut consumption on selenium status and cognitive performance in older adults with mild cognitive impairment: a randomized controlled pilot trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Biomarkers of selenium status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

The brain selenoproteome: priorities in the hierarchy and different levels of selenium homeostasis in the brain of selenium-deficient rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Regulation of ferroptotic cancer cell death by GPX4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Iron and dopamine: a toxic couple.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Protective effect of N-acetyl-L-cysteine against disulfiram-induced oxidative stress and apoptosis in V79 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Vitamin E and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Brain tocopherols related to Alzheimer's disease neuropathology in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Investigation of an albumin-enriched fraction of human serum and its albuminome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Tissue expression and cellular localization of phospholipid hydroperoxide glutathione peroxidase (PHGPx) mRNA in male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Site-Specific pKa Determination of Selenocysteine Residues in Selenovasopressin by Using 77Se NMR Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance.

21 January 2018

1 reference

12 December 2020

Oxidative stress in Alzheimer's disease and mild cognitive impairment with high sensitivity and specificity.

1 reference

12 December 2020

Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenate

1 reference

12 December 2020

Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells.

1 reference

12 December 2020

Functional diversity of cysteine residues in proteins and unique features of catalytic redox-active cysteines in thiol oxidoreductases

1 reference

12 December 2020

Gpx4 protects mitochondrial ATP generation against oxidative damage

1 reference

12 December 2020

Kinetic study of the reaction of glutathione peroxidase with peroxynitrite

1 reference

12 December 2020

Function of thioredoxin reductase as a peroxynitrite reductase using selenocystine or ebselen

1 reference

12 December 2020

Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells

1 reference

12 December 2020

Selenium status in elderly: relation to cognitive decline

1 reference

12 December 2020

Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs

1 reference

12 December 2020

Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis

1 reference

12 December 2020

Human [74Se]selenomethionine metabolism: a kinetic model

1 reference

12 December 2020

Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation

1 reference

12 December 2020

Protection by selenoprotein P in human plasma against peroxynitrite-mediated oxidation and nitration

1 reference

12 December 2020

Phospholipid-hydroperoxide glutathione peroxidase (GPx-4) localization in resting platelets, and compartmental change during platelet activation

1 reference

12 December 2020

Brazilian nut consumption improves selenium status and glutathione peroxidase activity and reduces atherogenic risk in obese women

1 reference

12 December 2020

Dietary reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids

1 reference

12 December 2020

Attenuation of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine induced nigrostriatal toxicity in mice by N-acetyl cysteine.

1 reference

12 December 2020

Differences in nutritional status between very mild Alzheimer's disease patients and healthy controls

1 reference

12 December 2020

Protection against peroxynitrite by selenoproteins.

1 reference

12 December 2020

Reactivity and ionization of the active site cysteine residues of DsbA, a protein required for disulfide bond formation in vivo

1 reference

12 December 2020

Effect of N-acetylcysteine on the spinal-cord glutathione system and nitric-oxide metabolites in rats with neuropathic pain

1 reference

12 December 2020

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.196

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/MP.2016.196

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27777421%20AND%20SRC:MED&resulttype=core&format=json

release_noufoqdbqff3po42cwup6q7twi

26 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/noufoqdbqff3po42cwup6q7twi

24 November 2022

mapped directly with Wikidata item

1 reference