Selective tumor cell killing by triptolide in p53 wild-type and p53 mutant ovarian carcinomas (Q38989751)

8 September 2017

Selective tumor cell killing by triptolide in p53 wild-type and p53 mutant ovarian carcinomas (English)

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8 September 2017

Jianyuan Wu

1

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8 September 2017

Qingdi Quentin Li

2

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8 September 2017

Huiping Zhou

3

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8 September 2017

Yinying Lu

4

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8 September 2017

Jueli M Li

5

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8 September 2017

Yao Ma

6

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8 September 2017

Li Wang

7

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8 September 2017

Tingting Fu

8

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8 September 2017

Xingjiang Gong

9

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8 September 2017

Michael Weintraub

10

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8 September 2017

Shuangchan Wu

11

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8 September 2017

Hong Ding

12

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8 September 2017

1 June 2014

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8 September 2017

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8 September 2017

31

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7

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https://scigraph.springernature.com/pub.10.1007/s12032-014-0014-8

8 September 2017

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EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice.

21 January 2018

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Triptolide and its expanding multiple pharmacological functions

21 January 2018

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Triptolide down-regulates bcr-abl expression and induces apoptosis in chronic myelogenous leukemia cells

21 January 2018

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PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2.

21 January 2018

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Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation

21 January 2018

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Antitumor activity of triptolide against cholangiocarcinoma growth in vitro and in hamsters

21 January 2018

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Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway

21 January 2018

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Inter-laboratory validation study of the Skin2 Dermal Model ZK1100 and MTT cytotoxicity assay kits

21 January 2018

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Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential

21 January 2018

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Multiparametric flow cytometric analysis in a breast cancer cell line (MCF-7).

21 January 2018

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A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage

21 January 2018

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Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase

21 January 2018

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Histone deacetylase inhibitors induce G2-checkpoint arrest and apoptosis in cisplatinum-resistant ovarian cancer cells associated with overexpression of the Bcl-2-related protein Bad.

21 January 2018

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Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation.

21 January 2018

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Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells

21 January 2018

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Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells.

21 January 2018

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A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia

21 January 2018

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Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release

21 January 2018

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Costimulation with interleukin-4 and interleukin-10 induces mast cell apoptosis and cell-cycle arrest: the role of p53 and the mitochondrion

21 January 2018

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Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway.

21 January 2018

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Cadmium induces caspase-mediated cell death: suppression by Bcl-2.

21 January 2018

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Inhibition of α‐ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase‐3 activation, and necrotic cell death

21 January 2018

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Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma

21 January 2018

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Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA.

21 January 2018

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RNA polymerase - an important molecular target of triptolide in cancer cells

21 January 2018

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Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

21 January 2018

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Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro

21 January 2018

1 reference

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Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.

21 January 2018

1 reference

12 December 2020

Inhibitory effect of triptolide on colony formation of breast and stomach cancer cell lines

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12 December 2020

The impact of p53 status on cellular sensitivity to antifolate drugs.

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12 December 2020

Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells

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12 December 2020

Unmasking of phosphorylation-sensitive epitopes on p53 and Mdm2 by a simple Western-phosphatase procedure

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12 December 2020

PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy.

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12 December 2020

Triptolide inhibits the growth and metastasis of solid tumors.

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12 December 2020

Nickel-induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects

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12 December 2020

Demonstration of differential gene expression between sensitive and resistant ovarian tumor cells by fluorescence differential display-PCR analysis.

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12 December 2020

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

1 reference

12 December 2020

10.1007/S12032-014-0014-8

Identifiers

DOI

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Dimensions Publication ID

8 September 2017

1048281656

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Fatcat ID

release_54be2lcacfgdplh4dpv6i6kadm

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Fatcat

https://api.fatcat.wiki/v0/release/54be2lcacfgdplh4dpv6i6kadm

24 November 2022

mapped directly with Wikidata item

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