A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes (Q38988228)

8 September 2017

A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes (English)

1 reference

8 September 2017

Mowat-Wilson syndrome

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Muna M El-Kasti

1

1 reference

PubMed ID

23001561

8 September 2017

Timothy Wells

series ordinal

2

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PubMed ID

23001561

8 September 2017

David A Carter

series ordinal

3

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8 September 2017

21 September 2012

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8 September 2017

Human Molecular Genetics

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8 September 2017

21

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8 September 2017

26

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8 September 2017

5429-5442

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New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites

8 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

The delta-crystallin enhancer-binding protein delta EF1 is a repressor of E2-box-mediated gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Organization of the mouse Zfhx1b gene encoding the two-handed zinc finger repressor Smad-interacting protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Pleiotropic and diverse expression of ZFHX1B gene transcripts during mouse and human development supports the various clinical manifestations of the "Mowat-Wilson" syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Stimulus-specific induction of an Egr-1 transgene in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Oestrogenic regulation of an egr-1 transgene in rat anterior pituitary

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Evolution and functional classification of vertebrate gene deserts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Generation and annotation of the DNA sequences of human chromosomes 2 and 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

RNA-Seq defines novel genes, RNA processing patterns and enhancer maps for the early stages of nephrogenesis: Hox supergenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

A regulatory archipelago controls Hox genes transcription in digits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

VISTA Enhancer Browser--a database of tissue-specific human enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Mapping and analysis of chromatin state dynamics in nine human cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

An Evolutionary Road Less Traveled: From Farming to Hunting and Gathering

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

A map of the cis-regulatory sequences in the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Evaluation of renal function in neonatal rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

"Avian-type" renal medullary tubule organization causes immaturity of urine-concentrating ability in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Postnatal expression of KLF12 in the inner medullary collecting ducts of kidney and its trans-activation of UT-A1 urea transporter promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Gender-specific and developmental influences on the expression of rat organic anion transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Enhancers: from developmental genetics to the genetics of common human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Integrative analysis of genomic, functional and protein interaction data predicts long-range enhancer-target gene interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Genomic views of distant-acting enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Ultraconserved Elements in the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Ultraconservation identifies a small subset of extremely constrained developmental enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

ChIP-seq accurately predicts tissue-specific activity of enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Landscapes and archipelagos: spatial organization of gene regulation in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for the pathogenesis of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

The role of the ZEB family of transcription factors in development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Mowat-Wilson syndrome: facial phenotype changing with age: study of 19 Italian patients and review of the literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Cytogenetic, FISH and array-CGH characterization of a complex chromosomal rearrangement carried by a mentally and language impaired patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Clinical and mutational spectrum of Mowat-Wilson syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Identification of de novo copy number variants associated with human disorders of sexual development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Egr-1-d2EGFP transgenic rats identify transient populations of neurons and glial cells during postnatal brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Selective genomic targeting by FRA-2/FOSL2 transcription factor: regulation of the Rgs4 gene is mediated by a variant activator protein 1 (AP-1) promoter sequence/CREB-binding protein (CBP) mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Transcription Mapping of Embryonic Rat Brain Reveals EGR-1 Induction in SOX2 Neural Progenitor Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS389

21 January 2018

Identifiers

DOI

10.1093/HMG/DDS389

1 reference

8 September 2017

1 reference

PubMed ID

23001561