How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro (Q38987375)

8 September 2017

How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro (English)

1 reference

8 September 2017

1 reference

12

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7 June 2020

Yuichi Yoshimura

3

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7 June 2020

Camilla B Andersen

5

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7 June 2020

Gunna Christiansen

8

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7 June 2020

Jan Skov Pedersen

9

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7 June 2020

Poul Henning Jensen

10

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7 June 2020

Frans A.A. Mulder

11

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7 June 2020

author name string

Nikolai Lorenzen

1

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7 June 2020

Søren B Nielsen

2

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7 June 2020

Brian S Vad

4

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7 June 2020

Cristine Betzer

6

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7 June 2020

Jørn D Kaspersen

7

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7 June 2020

language of work or name

English

0 references

publication date

6 June 2014

1 reference

Journal of Biological Chemistry

8 September 2017

1 reference

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7 June 2020

volume

289

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7 June 2020

issue

31

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7 June 2020

page(s)

21299-21310

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24907278%20AND%20SRC:MED&resulttype=core&format=json

The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

7 June 2020

cites work

1 reference

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α-Synuclein oligomers: an amyloid pore? Insights into mechanisms of α-synuclein oligomer-lipid interactions

9 September 2017

1 reference

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Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications

9 September 2017

1 reference

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Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

In vivo demonstration that alpha-synuclein oligomers are toxic

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation

9 September 2017

1 reference

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Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism

9 September 2017

1 reference

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Effects of Various Flavonoids on the α-Synuclein Fibrillation Process

9 September 2017

1 reference

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The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

9 September 2017

1 reference

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EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

9 September 2017

1 reference

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A synergistic small-molecule combination directly eradicates diverse prion strain structures

9 September 2017

1 reference

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Tryptophan fluorescence reveals structural features of alpha-synuclein oligomers

9 September 2017

1 reference

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Inhibition of alpha-synuclein fibrillization by dopamine is mediated by interactions with five C-terminal residues and with E83 in the NAC region

9 September 2017

1 reference

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Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Amyloid ion channels: a common structural link for protein-misfolding disease

9 September 2017

1 reference

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

9 September 2017

1 reference

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Solvent-induced collapse of alpha-synuclein and acid-denatured cytochrome c

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid giant unilamellar vesicles

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

9 September 2017

1 reference

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Alpha-synuclein in Lewy bodies

9 September 2017

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

9 September 2017

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

9 September 2017

1 reference

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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

9 September 2017

1 reference

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OLN-93: a new permanent oligodendroglia cell line derived from primary rat brain glial cultures

25 September 2017

1 reference

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Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils

25 September 2017

1 reference

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The influence of vesicle size and composition on alpha-synuclein structure and stability

17 June 2018

1 reference

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Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry.

17 June 2018

1 reference

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The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

21 August 2018

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Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry

21 August 2018

1 reference

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Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease.

21 August 2018

1 reference

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Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2.

21 August 2018

1 reference

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(-)-epigallocatechin-3-gallate (EGCG) maintains kappa-casein in its pre-fibrillar state without redirecting its aggregation pathway.

21 August 2018

1 reference

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Lipid bilayer disruption by oligomeric alpha-synuclein depends on bilayer charge and accessibility of the hydrophobic core.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Membrane binding of oligomeric alpha-synuclein depends on bilayer charge and packing

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Dopamine and L-dopa disaggregate amyloid fibrils: implications for Parkinson's and Alzheimer's disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118093

La diffraction des rayons X aux très petits angles : application à l'étude de phénomènes ultramicroscopiques

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.554667

Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24907278

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular-weight determination by light scattering

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24907278

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.554667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24907278%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24907278%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference