EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2. (Q38985433)

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English	EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2.	scientific article

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2. (English)

1 reference

Europe PubMed Central

8 September 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

cancer cell line

1 reference

based on heuristic

inferred from title

author name string

S Sangboonruang

1

1 reference

Europe PubMed Central

8 September 2017

P Thammasit

2

1 reference

Europe PubMed Central

8 September 2017

N Intasai

3

1 reference

Europe PubMed Central

8 September 2017

W Kasinrerk

4

1 reference

Europe PubMed Central

8 September 2017

C Tayapiwatana

5

1 reference

Europe PubMed Central

8 September 2017

K Tragoolpua

6

1 reference

Europe PubMed Central

8 September 2017

publication date

13 June 2014

1 reference

Europe PubMed Central

8 September 2017

Cancer Gene Therapy

1 reference

Europe PubMed Central

8 September 2017

21

1 reference

Europe PubMed Central

8 September 2017

6

1 reference

Europe PubMed Central

8 September 2017

246-255

1 reference

Europe PubMed Central

8 September 2017

https://scigraph.springernature.com/pub.10.1038/cgt.2014.24

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The discovery and validation of colorectal cancer biomarkers

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Role of emmprin/CD147 in tissue remodeling.

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CD147/basigin promotes progression of malignant melanoma and other cancers

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Overexpression of HAb18G/CD147 promotes invasion and metastasis via alpha3beta1 integrin mediated FAK-paxillin and FAK-PI3K-Ca2+ pathways

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

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21 January 2018

Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism

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21 January 2018

EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair.

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21 January 2018

Intrabodies as therapeutic agents

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Intrabody-based approaches to cancer therapy: status and prospects

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21 January 2018

The therapeutic potential of RNA interference

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21 January 2018

Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells

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Potent inhibition of OKT3-induced T cell proliferation and suppression of CD147 cell surface expression in HeLa cells by scFv-M6-1B9.

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ERAD: the long road to destruction

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beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide.

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Gene transfer to cervical cancer with fiber-modified adenoviruses

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Adenoviruses for treatment of cancer

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CD46 is a cellular receptor for group B adenoviruses

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Development of an adenoviral vector system with adenovirus serotype 35 tropism; efficient transient gene transfer into primary malignant hematopoietic cells

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Rearrangements in adenoviral genomes mediated by inverted repeats

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Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6

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21 January 2018

Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Inhibition of CD147 gene expression via RNA interference reduces tumor cell proliferation, activation, adhesion, and migration activity in the human Jurkat T-lymphoma cell line

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion

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21 January 2018

A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

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21 January 2018

Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

ERK1/2 signalling pathway is involved in CD147-mediated gastric cancer cell line SGC7901 proliferation and invasion

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21 January 2018

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

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21 January 2018

ERK1/2 MAP kinases in cell survival and apoptosis

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21 January 2018

Basigin (EMMPRIN/CD147) interacts with integrin to affect cellular architecture

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21 January 2018

Is overexpression of HER-2 a predictor of prognosis in colorectal cancer?

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21 January 2018

Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway

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21 January 2018

Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice

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21 January 2018

Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion.

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Insights into MMP-TIMP interactions.

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

New functions for the matrix metalloproteinases in cancer progression

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

RECK: a novel suppressor of malignancy linking oncogenic signaling to extracellular matrix remodeling

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21 January 2018

Degradation of urokinase plasminogen activator (UPA) in endometrial stromal cells requires both the UPA receptor and the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor

1 reference

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21 January 2018

EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Intracellular antibodies and challenges facing their use as therapeutic agents

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21 January 2018

RNA interference: potential therapeutic targets.

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis

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https://api.crossref.org/works/10.1038%2FCGT.2014.24

21 January 2018

Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures

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21 January 2018

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

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Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

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Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models

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21 January 2018

p38α MAPK mediates 17β-estradiol inhibition of MMP-2 and -9 expression and cell migration in human lovo colon cancer cells.

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21 January 2018

Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.

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21 January 2018

Housekeeping genes as internal standards in cancer research

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EMMPRIN (CD147) regulation of MMP-9 in bronchial epithelial cells in COPD

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12 December 2020

based on heuristic

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Downregulation of CD147 expression by RNA interference inhibits HT29 cell proliferation, invasion and tumorigenicity in vitro and in vivo.

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https://pubmed.ncbi.nlm.nih.gov/24924201

12 December 2020

based on heuristic

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Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions

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https://pubmed.ncbi.nlm.nih.gov/24924201

12 December 2020

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Gelatinases A and B (MMP-2 and MMP-9) in endometrial cancer-MMP-9 correlates to the grade and the stage

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12 December 2020

based on heuristic

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The interaction of HAb18G/CD147 with integrin alpha6beta1 and its implications for the invasion potential of human hepatoma cells

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12 December 2020

based on heuristic

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Cancer-related issues of CD147.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion

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12 December 2020

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Regulation of matrix metalloproteinases activity studied in human endometrium as a paradigm of cyclic tissue breakdown and regeneration

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12 December 2020

based on heuristic

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Identifiers

10.1038/CGT.2014.24

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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