Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin-neuraminidase inhibitors (Q38946739)

7 September 2017

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin-neuraminidase inhibitors (English)

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7 September 2017

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1

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6 June 2020

Larissa Dirr

2

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6 June 2020

Ibrahim M El-Deeb

3

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6 June 2020

Benjamin Bailly

5

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6 June 2020

Thomas Haselhorst

6

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6 June 2020

7

Jeffrey C Dyason

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6 June 2020

8

Mark von Itzstein

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6 June 2020

author name string

Moritz Winger

4

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6 June 2020

language of work or name

English

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publication date

20 October 2014

1 reference

7 September 2017

Nature Communications

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6 June 2020

volume

5

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6 June 2020

page(s)

5268

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https://scigraph.springernature.com/pub.10.1038/ncomms6268

6 June 2020

exact match

0 references

cites work

Parainfluenza viruses

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A daring treatment and a successful outcome: the need for targeted therapies for pediatric respiratory viruses.

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Evaluation of two chimeric bovine-human parainfluenza virus type 3 vaccines in infants and young children

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A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo

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Mechanism of fusion triggering by human parainfluenza virus type III: communication between viral glycoproteins during entry

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Entry of parainfluenza virus into cells as a target for interrupting childhood respiratory disease

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Human parainfluenza viruses hPIV1 and hPIV3 bind oligosaccharides with alpha2-3-linked sialic acids that are distinct from those bound by H5 avian influenza virus hemagglutinin

21 January 2018

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A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses.

21 January 2018

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Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein

21 January 2018

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Fusion promotion by a paramyxovirus hemagglutinin-neuraminidase protein: pH modulation of receptor avidity of binding sites I and II

21 January 2018

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Efficacy of novel hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 against human parainfluenza viruses in vitro and in vivo

21 January 2018

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Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity

21 January 2018

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Efficacy of the novel parainfluenza virus haemagglutinin-neuraminidase inhibitor BCX 2798 in mice - further evaluation

21 January 2018

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Effect of hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 on growth and pathogenicity of Sendai/human parainfluenza type 3 chimera virus in mice

21 January 2018

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Syntheses of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified by N-sulfonylamidino groups at the C-4 position and biological evaluation as inhibitors of human parainfluenza virus type 1.

21 January 2018

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Syntheses of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified by α-acylaminoamido groups at the C-4 position using isocyanide-based four-component coupling and biological evaluation as inhibitors of human parainfluenza virus type 1.

21 January 2018

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Exposing the flexibility of human parainfluenza virus hemagglutinin-neuraminidase

21 January 2018

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Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III

21 January 2018

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Synthesis of C-4 and C-7 triazole analogs of zanamivir as multivalent sialic acid containing scaffolds

21 January 2018

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Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.

21 January 2018

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Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-alpha-D-N-acetylneuraminate) substrate

21 January 2018

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The anti-influenza virus agent 4-GU-DANA (zanamivir) inhibits cell fusion mediated by human parainfluenza virus and influenza virus HA.

21 January 2018

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Inhibition of human parainfluenza virus type 1 sialidase by analogs of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid

21 January 2018

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Receptor specificities of human respiroviruses

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Analysis of influenza virus hemagglutinin receptor binding mutants with limited receptor recognition properties and conditional replication characteristics

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Inhibition of human parainfluenza virus-3 replication by interferon and human MxA.

21 January 2018

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Definition and testing of the GROMOS force-field versions 54A7 and 54B7

21 January 2018

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A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

21 January 2018

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

21 January 2018

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Recognition of the GM3 ganglioside glycan by Rhesus rotavirus particles

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6268

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6268

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25327774%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

ADS bibcode

2014NatCo...5.5268G

0 references

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1 reference

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