Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients. (Q38942785)

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22 February 2020

title

Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients (English)

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22 February 2020

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8

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Richard F. Kefford

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22 February 2020

Georgina V. Long

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22 February 2020

Helen Rizos

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1

Matteo S Carlino

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22 February 2020

2

Carina Fung

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5

Suzanah C Boyd

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22 February 2020

3

Hamideh Shahheydari

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Adnan M Nagrial

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author name string

Jason R Todd

4

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22 February 2020

Mal Irvine

6

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language of work or name

English

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publication date

4 November 2014

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22 February 2020

published in

Clinical Cancer Research

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volume

21

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issue

1

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page(s)

98-105

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

22 February 2020

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE09626

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/J.CCR.2010.11.023

Identifiers

DOI

10.1158/1078-0432.CCR-14-0759

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22 February 2020

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