HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma (Q38918235)

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English	HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma	scientific article

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scholarly article

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Europe PubMed Central

7 September 2017

HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma (English)

1 reference

Europe PubMed Central

7 September 2017

B-cell lymphoma

1 reference

based on heuristic

inferred from title

diffuse large B-cell lymphoma

1 reference

based on heuristic

inferred from title

Mahesh B. Chandrasekharan

11

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31 May 2020

author name string

Danielle P Johnson

1

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31 May 2020

Gabriella S Spitz

2

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31 May 2020

Shweta Tharkar

3

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31 May 2020

Steven N Quayle

4

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31 May 2020

Jeffrey R Shearstone

5

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31 May 2020

Simon Jones

6

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31 May 2020

Maria E McDowell

7

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31 May 2020

Hannah Wellman

8

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31 May 2020

Jessica K Tyler

9

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31 May 2020

Bradley R Cairns

10

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31 May 2020

Srividya Bhaskara

12

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31 May 2020

language of work or name

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publication date

1 March 2015

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Europe PubMed Central

7 September 2017

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31 May 2020

6

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31 May 2020

4863-4887

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31 May 2020

7

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31 May 2020

describes a project that uses

object named as

DESeq

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.

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9 September 2017

3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation

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9 September 2017

Transcription and beyond: the role of mammalian class I lysine deacetylases

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9 September 2017

EZH2 in normal and malignant hematopoiesis

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9 September 2017

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma

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9 September 2017

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

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9 September 2017

HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses

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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

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Histone chaperones in nucleosome assembly and human disease

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9 September 2017

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

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9 September 2017

BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8

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9 September 2017

The emerging role of Polycomb repressors in the response to DNA damage

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9 September 2017

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467121

9 September 2017

Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells.

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9 September 2017

Playing the end game: DNA double-strand break repair pathway choice

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9 September 2017

Relapsed/refractory diffuse large B-cell lymphoma

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9 September 2017

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment

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Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells

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Histone deacetylase inhibitors in the treatment of hematological malignancies.

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Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness".

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9 September 2017

Hdac3 is essential for the maintenance of chromatin structure and genome stability

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9 September 2017

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

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9 September 2017

Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis

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9 September 2017

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

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9 September 2017

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

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9 September 2017

BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response

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9 September 2017

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

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9 September 2017

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

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Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

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Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

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9 September 2017

The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity

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9 September 2017

BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration

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9 September 2017

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14 September 2017

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17 June 2018

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Identifiers

10.18632/ONCOTARGET.3120

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31 May 2020

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