Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. (Q38897786)

7 September 2017

Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. (English)

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7 September 2017

15

Ki Won Lee

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7 September 2017

14

Hyong Joo Lee

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7 September 2017

Ji Hoon Lee

1

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7 September 2017

Jong-Eun Kim

2

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7 September 2017

Young Jin Jang

3

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7 September 2017

Charles C Lee

4

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7 September 2017

Tae-Gyu Lim

5

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7 September 2017

Sung Keun Jung

6

1 reference

7 September 2017

Eunjung Lee

7

1 reference

7 September 2017

Soon Sung Lim

8

1 reference

7 September 2017

Yong Seok Heo

9

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7 September 2017

Sang Gwon Seo

10

1 reference

7 September 2017

Joe Eun Son

11

1 reference

7 September 2017

Jong Rhan Kim

12

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7 September 2017

Chang Yong Lee

13

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7 September 2017

18 March 2015

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7 September 2017

Molecular Carcinogenesis

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7 September 2017

55

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7 September 2017

5

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7 September 2017

552-562

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Molecular and cellular targets

7 September 2017

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Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis

21 January 2018

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Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis

21 January 2018

1 reference

The roles of polyphenols in cancer chemoprevention

21 January 2018

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

21 January 2018

1 reference

Mechanism of p38 MAP kinase activation in vivo.

21 January 2018

1 reference

Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-kappaB signaling in human epidermal keratinocytes

21 January 2018

1 reference

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 January 2018

1 reference

Exploiting the PI3K/AKT pathway for cancer drug discovery

21 January 2018

1 reference

Antibacterial compounds from Glycyrrhiza uralensis

21 January 2018

1 reference

Antioxidant activities of licorice-derived prenylflavonoids

21 January 2018

1 reference

Cocoa polyphenols suppress TNF-α-induced vascular endothelial growth factor expression by inhibiting phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase kinase-1 (MEK1) activities in mouse epidermal cells

21 January 2018

1 reference

Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats

21 January 2018

1 reference

Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway

21 January 2018

1 reference

Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice

21 January 2018

1 reference

Inhibitory effects of licochalcone A isolated from Glycyrrhiza inflata root on inflammatory ear edema and tumour promotion in mice

21 January 2018

1 reference

Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development

21 January 2018

1 reference

Protection against benzo[a]pyrene- and N-nitrosodiethylamine-induced lung and forestomach tumorigenesis in A/J mice by water extracts of green tea and licorice.

21 January 2018

1 reference

Inhibition of mutagenicity in Salmonella typhimurium and skin tumor initiating and tumor promoting activities in SENCAR mice by glycyrrhetinic acid: comparison of 18 alpha- and 18 beta-stereoisomers.

21 January 2018

1 reference

Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds

21 January 2018

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21 January 2018

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Dehydroglyasperin C, a component of liquorice, attenuates proliferation and migration induced by platelet-derived growth factor in human arterial smooth muscle cells

21 January 2018

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Neuroprotective effects of dehydroglyasperin C through activation of heme oxygenase-1 in mouse hippocampal cells

21 January 2018

1 reference

Myricetin suppresses UVB-induced skin cancer by targeting Fyn.

21 January 2018

1 reference

21 January 2018

Inflammation and cancer

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NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells

21 January 2018

1 reference

Crystal structures of MKK4 kinase domain reveal that substrate peptide binds to an allosteric site and induces an auto-inhibition state

21 January 2018

1 reference

Molecular targets of phytochemicals for cancer prevention

21 January 2018

1 reference

From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage.

21 January 2018

1 reference

Sorafenib and sunitinib: novel targeted therapies for renal cell cancer

21 January 2018

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Role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma

21 January 2018

1 reference

Signal transduction pathways: targets for chemoprevention of skin cancer

21 January 2018

1 reference

Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

21 January 2018

1 reference

AP-1: a double-edged sword in tumorigenesis

21 January 2018

1 reference

NF-kappa B as a target for cancer therapy

21 January 2018

1 reference

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.

21 January 2018

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A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression

21 January 2018

1 reference

Signal transduction pathways in cancer development and as targets for cancer prevention

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MC.22302

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7 September 2017

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