Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance (Q38884686)

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English	Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance	scientific article

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scholarly article

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Europe PubMed Central

7 September 2017

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance (English)

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Europe PubMed Central

7 September 2017

clear cell carcinoma

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based on heuristic

inferred from title

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based on heuristic

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2

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9 June 2020

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9 June 2020

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9 June 2020

Jermaine I Coward

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C B Gilks

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9 June 2020

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Y He

1

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9 June 2020

B S Harrington

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9 June 2020

C M Davies

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9 June 2020

S J Wallace

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9 June 2020

J S Palmer

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9 June 2020

D K Roche

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9 June 2020

B G Hollier

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9 June 2020

T F Westbrook

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9 June 2020

H Hamidi

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9 June 2020

G E Konecny

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9 June 2020

B Winterhoff

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9 June 2020

A J Crandon

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9 June 2020

C M Shannon

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9 June 2020

A V Tinker

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9 June 2020

J W Lumley

21

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9 June 2020

J E Armes

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9 June 2020

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publication date

20 April 2015

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7 September 2017

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468-478

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4

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9 June 2020

https://scigraph.springernature.com/pub.10.1038/onc.2015.101

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Global cancer statistics

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

New perspectives on molecular targeted therapy in ovarian clear cell carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers

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https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Exploring palliative treatment outcomes in women with advanced or recurrent ovarian clear cell carcinoma

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https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Ovarian cancer development and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Mechanisms of transcoelomic metastasis in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells

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21 January 2018

A mouse knockout library for secreted and transmembrane proteins.

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21 January 2018

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential

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https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration

1 reference

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21 January 2018

Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.

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21 January 2018

Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Targeting pathways contributing to epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

An evaluation of cytotoxicity of the taxane and platinum agents combination treatment in a panel of human ovarian carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers

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21 January 2018

The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1.

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21 January 2018

Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration

1 reference

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21 January 2018

Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model

1 reference

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21 January 2018

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.101

21 January 2018

Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids

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21 January 2018

Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer

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21 January 2018

Cell cycle arrest or survival signaling through αv integrins, activation of PKC and ERK1/2 lead to anoikis resistance of ovarian cancer spheroids.

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21 January 2018

Low-stage ovarian clear cell carcinoma: population-based outcomes in British Columbia, Canada, with evidence for a survival benefit as a result of irradiation

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31 March 2020

Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma

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31 March 2020

Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy

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https://pubmed.ncbi.nlm.nih.gov/25893298

12 December 2020

based on heuristic

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Update on first-line treatment of advanced ovarian carcinoma

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https://pubmed.ncbi.nlm.nih.gov/25893298

12 December 2020

based on heuristic

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Glutathione peroxidase 3 is a candidate mechanism of anticancer drug resistance of ovarian clear cell adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/25893298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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