ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation. (Q38875257)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

author name string

Thomas J Nelson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Daniel L Alkon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

language of work or name

English

0 references

publication date

1 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

7538-7551

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

8 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6705431/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease.

1 reference

12 December 2020

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

1 reference

12 December 2020

Neurotrophic factors in Alzheimer's and Parkinson's disease brain

1 reference

12 December 2020

Total number and distribution of inhibitory and excitatory synapses on hippocampal CA1 pyramidal cells

1 reference

12 December 2020

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

12 December 2020

Allosteric modulation of ligand binding to low density lipoprotein receptor-related protein by the receptor-associated protein requires critical lysine residues within its carboxyl-terminal domain.

1 reference

12 December 2020

Cholesterol homeostasis and function in neurons of the central nervous system

1 reference

12 December 2020

Regulation of histone acetylation during memory formation in the hippocampus.

1 reference

12 December 2020

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

1 reference

12 December 2020

Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.

1 reference

12 December 2020

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

1 reference

12 December 2020

HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis.

1 reference

12 December 2020

Low density lipoprotein receptor-related proteins (LRPs), Alzheimer's and cognition

1 reference

12 December 2020

Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.

1 reference

12 December 2020

Mouse and rat BDNF gene structure and expression revisited

1 reference

12 December 2020

Recovery of learning and memory is associated with chromatin remodelling

1 reference

12 December 2020

Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear

1 reference

12 December 2020

Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters

1 reference

12 December 2020

GABA(A) receptors in aging and Alzheimer's disease

1 reference

12 December 2020

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

1 reference

12 December 2020

APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway

1 reference

12 December 2020

Analyzing real-time PCR data by the comparative C(T) method

1 reference

12 December 2020

Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons

1 reference

12 December 2020

Histone deacetylase 6 interacts with the microtubule-associated protein tau

1 reference

12 December 2020

Genetic and epigenetic defects in mental retardation.

1 reference

12 December 2020

Neuroprotective versus tumorigenic protein kinase C activators

1 reference

12 December 2020

Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex.

1 reference

12 December 2020

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

1 reference

12 December 2020

Regulation of secretases by all-trans-retinoic acid

1 reference

12 December 2020

Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise

1 reference

12 December 2020

Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.

1 reference

12 December 2020

Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators

1 reference

12 December 2020

GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice

1 reference

12 December 2020

Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells

1 reference

12 December 2020

Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2.

1 reference

12 December 2020

Targeting the correct HDAC(s) to treat cognitive disorders

1 reference

12 December 2020

PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice

1 reference

12 December 2020

Apolipoprotein E in Alzheimer's disease and other neurological disorders

1 reference

12 December 2020

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease

1 reference

12 December 2020

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders.

1 reference

12 December 2020

Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments

1 reference

12 December 2020

Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants

1 reference

12 December 2020

An epigenetic blockade of cognitive functions in the neurodegenerating brain

1 reference

12 December 2020

Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease

1 reference

12 December 2020

Apolipoprotein E3 (ApoE3) but not ApoE4 protects against synaptic loss through increased expression of protein kinase C epsilon

1 reference

12 December 2020

The neurotrophins and their role in Alzheimer's disease

1 reference

12 December 2020

Loss of functional GABA(A) receptors in the Alzheimer diseased brain

1 reference

12 December 2020

Protein kinase C stimulates HuD-mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture

1 reference

12 December 2020

Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice.

1 reference

12 December 2020

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

1 reference

12 December 2020

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

1 reference

12 December 2020

Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy

1 reference

12 December 2020

PKC activation during training restores mushroom spine synapses and memory in the aged rat

1 reference

12 December 2020

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein

1 reference

12 December 2020

The role of ATM and DNA damage in neurons: upstream and downstream connections.

1 reference

12 December 2020

Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.

1 reference

12 December 2020

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

1 reference

12 December 2020

Additive genetic effect of APOE and BDNF on hippocampus activity.

1 reference

12 December 2020

Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus

1 reference

12 December 2020

Apathy and APOE4 are associated with reduced BDNF levels in Alzheimer's disease

1 reference

12 December 2020

PKCε deficits in Alzheimer's disease brains and skin fibroblasts

1 reference

12 December 2020

APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease

1 reference

12 December 2020

APOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease.

1 reference

12 December 2020

Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice

1 reference

12 December 2020

Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection

1 reference

12 December 2020

Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site

1 reference

12 December 2020

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

1 reference

12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

12 December 2020

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

12 December 2020

Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease

1 reference

12 December 2020

Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli

1 reference

12 December 2020

ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families

1 reference

12 December 2020

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

12 December 2020

The carboxyl terminus in apolipoprotein E2 and the seven amino acid repeat in apolipoprotein E-Leiden: role in receptor-binding activity.

1 reference

12 December 2020

10.1523/JNEUROSCI.0260-15.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972179%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference