miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model. (Q38862227)

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17 February 2020

title

miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model (English)

1 reference

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17 February 2020

0 references

1 reference

chronic lymphocytic leukemia

1 reference

inferred from title

author

Maria Grazia Narducci

7

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17 February 2020

Giandomenico Russo

12

1 reference

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17 February 2020

Massimo Negrini

13

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17 February 2020

10

Carlo M Croce

1 reference

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17 February 2020

8

Elisabetta Caprini

1 reference

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17 February 2020

1

Antonella Bresin

1 reference

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17 February 2020

author name string

Elisa Callegari

2

1 reference

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17 February 2020

Lucilla D'Abundo

3

1 reference

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17 February 2020

Caterina Cattani

4

1 reference

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17 February 2020

Cristian Bassi

5

1 reference

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17 February 2020

Barbara Zagatti

6

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17 February 2020

Yuri Pekarsky

9

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17 February 2020

Silvia Sabbioni

11

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17 February 2020

language of work or name

English

0 references

publication date

1 August 2015

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17 February 2020

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17 February 2020

volume

6

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17 February 2020

issue

23

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17 February 2020

page(s)

19807-19818

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Progress in the treatment of elderly/unfit chronic lymphocytic leukemia patients: results of the German CLL-11 trial

17 February 2020

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miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes

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miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes.

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miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia

9 September 2017

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Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia

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The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

9 September 2017

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Karyotype-specific microRNA signature in chronic lymphocytic leukemia

9 September 2017

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microRNAs and their potential target genes in leukemia pathogenesis

9 September 2017

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Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?

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9 September 2017

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Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181

9 September 2017

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B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia

9 September 2017

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A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

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9 September 2017

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9 September 2017

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Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

9 September 2017

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Identification of the TCL1 gene involved in T-cell malignancies

9 September 2017

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9 September 2017

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miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines

9 September 2017

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

14 September 2017

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

14 September 2017

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A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways

14 September 2017

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Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

14 September 2017

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Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

14 September 2017

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Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

14 September 2017

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bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

17 June 2018

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Establishment of a karyotypically normal B-chronic lymphocytic leukemia cell line; evidence of leukemic origin by immunoglobulin gene rearrangement

17 June 2018

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Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy

17 June 2018

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B-cell receptor signaling in chronic lymphocytic leukemia.

22 August 2018

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CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation

22 August 2018

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Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells.

22 August 2018

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Systemic delivery of DNA or siRNA mediated by linear polyethylenimine (L-PEI) does not induce an inflammatory response

22 August 2018

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Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice

22 August 2018

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ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

22 August 2018

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Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta.

22 August 2018

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microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters

22 August 2018

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TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state

22 August 2018

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12 December 2020

Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues

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12 December 2020

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

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12 December 2020

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12 December 2020

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

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12 December 2020

Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion

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12 December 2020

Survival of leukemic B cells promoted by engagement of the antigen receptor

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12 December 2020

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

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12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.4415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090867%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090867%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090867%20AND%20SRC:MED&resulttype=core&format=json