Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria. (Q38852851)

7 September 2017

Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria (English)

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Andrea Conroy

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13 May 2020

John G Hay

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13 May 2020

Kevin C Kain

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13 May 2020

author name string

Sarah J Higgins

1

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13 May 2020

Lisa A Purcell

2

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13 May 2020

Karlee L Silver

3

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13 May 2020

Michael Hawkes

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Susan E Quaggin

10

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Gavin Thurston

11

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13 May 2020

W Conrad Liles

12

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13 May 2020

Vanessa Tran

4

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Robert O Opoka

8

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13 May 2020

language of work or name

English

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publication date

1 September 2016

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Science Translational Medicine

7 September 2017

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13 May 2020

volume

8

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issue

358

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page(s)

358ra128

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Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013: Findings From the Global Burden of Disease 2013 Study

13 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Piecing together the puzzle of severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Malaria biology and disease pathogenesis: insights for new treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Development, maintenance and disruption of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

The neuropathology of fatal cerebral malaria in malawian children

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Brain swelling and death in children with cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietin-1 protects the adult vasculature against plasma leakage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

A rapid murine coma and behavior scale for quantitative assessment of murine cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Neuroimmunological blood brain barrier opening in experimental cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Dysregulation of the angiopoietin-Tie-2 axis in sepsis and ARDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Innate immunity to malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

The complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Gene control of tyrosine kinase TIE2 and vascular manifestations of infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Collateral density, remodeling, and VEGF-A expression differ widely between mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF6812

Inflammatory cytokines and vascular endothelial growth factor stimulate the release of soluble tie receptor from human endothelial cells via metalloprotease activation

21 January 2018

1 reference

12 December 2020

Thrombin induces the release of angiopoietin-1 from platelets.

1 reference

12 December 2020

Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury

1 reference

12 December 2020

Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition

1 reference

12 December 2020

10.1126/SCITRANSLMED.AAF6812

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6450386&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6450386&resulttype=core&format=json

13 May 2020

1 reference