The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections (Q38837353)

6 September 2017

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections (English)

1 reference

6 September 2017

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Tim Felton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Juergen Bulitta

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Matteo Bassetti

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

T Tängdén

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

V Ramos Martín

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

E I Nielsen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

S Marchand

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

R J Brüggemann

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

U Theuretzbacher

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

B T Tsuji

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

D W Wareham

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

L E Friberg

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

J J De Waele

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

V H Tam

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Infection Section for the European Society of Intensive Care Medicine, the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious Diseases, the International Society of Anti-Infective Pharmacology and the Critically Ill Patients Study Group of European Society of Clinical Microbiology and Infectious Diseases

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

13 April 2017

1 reference

6 September 2017

Intensive Care Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

1021-1032

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00134-017-4780-6

6 June 2020

exact match

0 references

cites work

Impact of Policies on the Rise in Sepsis Incidence, 2000-2010

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

International study of the prevalence and outcomes of infection in intensive care units

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Clinical implications of antibiotic pharmacokinetic principles in the critically ill.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacological indices in antibiotic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Clinically relevant plasma concentrations of colistin in combination with imipenem enhance pharmacodynamic activity against multidrug-resistant Pseudomonas aeruginosa at multiple inocula

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

In vitro pharmacodynamic models to determine the effect of antibacterial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: a new paradigm for optimizing pharmacodynamics to counterselect resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacodynamics of early, high-dose linezolid against vancomycin-resistant enterococci with elevated MICs and pre-existing genetic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Augmented renal clearance: implications for antibacterial dosing in the critically ill.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Principles of antibacterial dosing in continuous renal replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Antifungal pharmacokinetics and pharmacodynamics: bridging from the bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Population pharmacokinetics of teicoplanin in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Optimal sampling schedule design for populations of patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Tissue concentrations: do we ever learn?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Microdialysis as a way to measure antibiotics concentration in tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Kinetics of imipenem distribution into the peritoneal fluid of patients with severe peritonitis studied by microdialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Penetration of gentamicin into the alveolar lining fluid of critically ill patients with ventilator-associated pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Plasma and lung concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Penetration of meropenem into pneumonic human lung tissue as measured by in vivo microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Penetration of piperacillin and tazobactam into pneumonic human lung tissue measured by in vivo microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

A pilot study testing whether concentrations of levofloxacin in interstitial space fluid of soft tissues may serve as a surrogate for predicting its pharmacokinetics in lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Analysis of vancomycin entry into pulmonary lining fluid by bronchoalveolar lavage in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Tissue penetration and pharmacokinetics of tigecycline in diabetic patients with chronic wound infections described by using in vivo microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

In vivo microdialysis study of the penetration of daptomycin into soft tissues in diabetic versus healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Interpreting population pharmacokinetic-pharmacodynamic analyses - a clinical viewpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Fundamentals of Population Pharmacokinetic Modelling : Modelling and Software

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Use of preclinical data for selection of a phase II/III dose for evernimicin and identification of a preclinical MIC breakpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Simulation-Based Evaluation of PK/PD Indices for Meropenem Across Patient Groups and Experimental Designs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Clinical pharmacodynamics of meropenem in patients with lower respiratory tract infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Penetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Cefepime free minimum concentration to minimum inhibitory concentration (fCmin/MIC) ratio predicts clinical failure in patients with Gram-negative bacterial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Toxicodynamics of itraconazole: implications for therapeutic drug monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Are vancomycin trough concentrations adequate for optimal dosing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

What about confidence intervals? A word of caution when interpreting PTA simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Vancomycin dosing in critically ill patients: robust methods for improved continuous-infusion regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

New Regimen for Continuous Infusion of Vancomycin in Critically Ill Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Therapeutic drug monitoring of anti-infective agents in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Combination therapy for carbapenem-resistant Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Front-loaded linezolid regimens result in increased killing and suppression of the accessory gene regulator system of Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Population pharmacokinetics of fusidic acid: rationale for front-loaded dosing regimens due to autoinhibition of clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Relationship between initial vancomycin concentration-time profile and nephrotoxicity among hospitalized patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Daptomycin exposure and the probability of elevations in the creatine phosphokinase level: data from a randomized trial of patients with bacteremia and endocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Clinical population pharmacokinetics and toxicodynamics of linezolid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Efficacy, nephrotoxicity and ototoxicity of aminoglycosides, mathematically modelled for modelling-supported therapeutic drug monitoring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Population pharmacokinetic and pharmacodynamic analysis of linezolid and a hematologic side effect, thrombocytopenia, in Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Population pharmacokinetics and pharmacodynamics of teicoplanin in neonates: making better use of C-reactive protein to deliver individualized therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-017-4780-6

Tree-Based Models for Predicting Mortality in Gram-Negative Bacteremia: Avoid Putting the CART before the Horse.

21 January 2018

1 reference

12 December 2020

The impact of multidrug resistance on the outcomes of critically ill patients with Gram-negative bacterial pneumonia

1 reference

12 December 2020

An artificial capillary in vitro kinetic model of antibiotic bactericidal activity

1 reference

12 December 2020

Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis

1 reference

12 December 2020

A problem in the interpretation of beta-lactam antibiotic levels in tissues

1 reference

12 December 2020

Use of C-reactive protein to guide duration of empiric antibiotic therapy in suspected early neonatal sepsis

1 reference

12 December 2020

10.1007/S00134-017-4780-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28409203%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference