MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation (Q38829973)

6 September 2017

MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation (English)

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6 September 2017

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Durga Nand Tripathi

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Gautam Borthakur

series ordinal

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object named as

Gautam Borthakur

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11

Marina Konopleva

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12

Michael Andreeff

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6 September 2017

7

Rodrigo Jacamo

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9

Peter Ruvolo

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3

Vivian Ruvolo

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6 September 2017

2

Seshagiri Duvvuri

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6

Jared Burks

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6 September 2017

Sujan Piya

5

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6 September 2017

Kensuke Kojima

series ordinal

8

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6 September 2017

Juan Fueyo-Margareto

series ordinal

10

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6 September 2017

language of work or name

English

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publication date

6 October 2015

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6 September 2017

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6 September 2017

10

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6 September 2017

e0139254

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Creative Commons Attribution 4.0 International

6 September 2017

start time

6 October 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

9 September 2017

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9 September 2017

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

9 September 2017

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9 September 2017

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Regulation of autophagy by cytoplasmic p53

9 September 2017

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9 September 2017

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

9 September 2017

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

9 September 2017

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

9 September 2017

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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

9 September 2017

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The coordinate regulation of the p53 and mTOR pathways in cells

9 September 2017

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

9 September 2017

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Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

9 September 2017

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Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

9 September 2017

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Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase

9 September 2017

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Mammalian AMP-activated protein kinase subfamily

9 September 2017

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

9 September 2017

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9 September 2017

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p53: The Janus of autophagy?

25 September 2017

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Influence of schedule on regulated sensitivity of AML blasts to cytosine arabinoside

17 June 2018

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17 June 2018

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Assays to assess autophagy induction and fusion of autophagic vacuoles with a degradative compartment, using monodansylcadaverine (MDC) and DQ-BSA.

22 August 2018

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The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.

22 August 2018

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Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.

22 August 2018

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Mitophagy: the life-or-death dichotomy includes yeast

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26440941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0139254

1 reference

6 September 2017

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1 reference

6 September 2017

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