Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis (Q38816682)

6 September 2017

title

Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis (English)

1 reference

Vaithilingaraja Arumugaswami

6 September 2017

1 reference

15

object named as

Vaithilingaraja Arumugaswami

1 reference

6 September 2017

14

Moshe Arditi

1 reference

6 September 2017

Nicole Ehrhardt

1

1 reference

6 September 2017

Michael E Doche

2

1 reference

6 September 2017

Shuang Chen

3

1 reference

6 September 2017

Hui Z Mao

4

1 reference

6 September 2017

Meghan T Walsh

5

1 reference

6 September 2017

Candy Bedoya

6

1 reference

6 September 2017

Maha Guindi

7

1 reference

6 September 2017

Weidong Xiong

8

1 reference

6 September 2017

Joseph Ignatius Irudayam

9

1 reference

6 September 2017

Jahangir Iqbal

10

1 reference

6 September 2017

Sebastien Fuchs

11

1 reference

6 September 2017

Samuel W French

12

1 reference

6 September 2017

M Mahmood Hussain

13

1 reference

6 September 2017

Miklós Péterfy

16

1 reference

6 September 2017

publication date

25 April 2017

1 reference

6 September 2017

published in

Human Molecular Genetics

1 reference

6 September 2017

volume

26

1 reference

6 September 2017

issue

14

1 reference

6 September 2017

page(s)

2719-2731

1 reference

Discovery and refinement of loci associated with lipid levels

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

The impact of low-frequency and rare variants on lipid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

TM6SF2 rs58542926 impacts lipid processing in liver and small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Meta-analysis of the influence of TM6SF2 E167K variant on Plasma Concentration of Aminotransferases across different Populations and Diverse Liver Phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Hepatic Transmembrane 6 Superfamily Member 2 Regulates Cholesterol Metabolism in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins--brief report

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Gene overexpression: uses, mechanisms, and interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Chorioamnionitis induced hepatic inflammation and disturbed lipid metabolism in fetal sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Intracellular trafficking and secretion of VLDL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

Measurement of apolipoprotein B in various cell lines: correlation between intracellular levels and rates of secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX159

TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

A simple method for the isolation and purification of total lipides from animal tissues

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

Hepatic lipase overexpression lowers remnant and LDL levels by a noncatalytic mechanism in LDL receptor-deficient mice

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

High density lipoprotein metabolism.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5886214

Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28449094

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28449094

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDX159

1 reference

6 September 2017

0 references

1 reference